Gastroesophageal polyp diagnosed in an adolescent presenting with epigastric pain

Stafford, Elisabeth M.; Imai, Walter K.

doi:10.1016/0197-0070(87)90234-8

Cited by 10 publications

(12 citation statements)

References 5 publications

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“…In children, only 10 articles including 15 cases have been reported in the medical literature [1,3,5,8,12,14,15,16,17,19]. H2 blockers have been used as the treatment of choice in most cases.…”

Section: Discussionmentioning

confidence: 99%

“…H2 blockers and/or PPI medication, endoscopic mucosal resection, endoscopic polypectomy, excision of the polyp, and fundoplication have been suggested as treatment modalities for IEPs [1,3,5,6,8,12,13,14,15,16,17,18,19,20,21,22,23]. Controlling reflux esophagitis can reduce the polyp size and decrease the clinical symptoms [3,16,17,24]; however, it is difficult to determine which medication is optimal and how long medication is needed for treatment.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Proton Pump Inhibitors on Pediatric Inflammatory Esophagogastric Polyps

Choi

Kim²,

Lee³

et al. 2012

Digestion

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Background: The aim of this study was to investigate the effects of proton pump inhibitors on symptomatic inflammatory esophagogastric polyps (IEPs) in a pediatric cohort and to determine the optimal duration of treatment. Methods: The 11 patients with IEPs were managed with lansoprazole. Follow-up endoscopies were performed at 2 and 6 months after the start of medication. Medication was discontinued when the clinical symptoms completely resolved and the polyp size was reduced by more than 50% compared to the initial size. Results:The initial polyp size was 13.7 ± 3.3 mm. After 2 months of medication, the polyp size was reduced to 8.0 ± 5.8 mm. At 6 months, the polyp size was 4.7 ± 2.2 mm. The mean duration of medication was 4.8 ± 2.1 months. The duration of medication and the change in the polyp size appeared to have a linear correlation (p < 0.001). According to the formula used to calculate polyp size, the optimal duration of treatment was more than 7 months for complete resolution of the polyps. Conclusions: Proton pump inhibitor was effective for the treatment of IEPs. About 5 months of lansoprazole was adequate to treat IEPs in children. The optimal duration for complete resolution of the polyp might be more than 7 months.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effects of Proton Pump Inhibitors on Pediatric Inflammatory Esophagogastric Polyps

Choi

Kim²,

Lee³

et al. 2012

Digestion

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“…There was a male predominance (10/13). Most patients (12) were Caucasian, one was African-American. On endoscopic examination, one subject had multiple polyps (3) described, the other 12 patients had only a solitary polyp.…”

Section: Clinical and Endoscopic Findingsmentioning

confidence: 99%

“…Several papers have described esophageal polyps in adults . Published reports on esophageal polyps in children have been limited to case reports …”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4][5][6] Published reports on esophageal polyps in children have been limited to case reports. [7][8][9][10][11][12][13] Broadly defined, an esophageal polyp is any intraluminal projection of tissue in the esophagus, this generally excludes extrinsic compression. Histopathologic descriptions for esophageal polyps have included squamous papillomas, 14 giant fibrovascular polyps, [15][16][17] lipomas, 18 inflammatory fibroid polyps, 19,20 hamartomas, 21 primary glomangioma 22 and pyogenic granulomas.…”

Section: Introductionmentioning

confidence: 99%

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Esophageal polyps in pediatric patients undergoing routine diagnostic upper gastrointestinal endoscopy: a multicenter study

Septer

Cuffari²,

Attard

2013

Dis Esophagus

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Esophageal polyps are uncommon findings in pediatric patients, and reports have been limited to case reports. Esophageal polyps have been previously ascribed to esophagitis secondary to gastroesophageal reflux, medications, infections and recurrent vomiting. They have been associated with underlying conditions such as hiatal hernia, Barrett's esophagus, eosinophilic esophagitis and Crohn's disease. Presenting complaints of children with esophageal polyps have included vomiting, dysphagia, hematemesis and abdominal pain. The aim of this paper is to characterize the incidence, clinical presentation and progression, histologic subtypes and associated mucosal abnormalities in children with esophageal polyps. A retrospective multicenter study was performed at four institutions identifying diagnosis of esophageal polyps in pediatric patients (<21 years). Information was obtained from patient charts, endoscopy reports and histopathology reports. Specimens and slides were examined by experienced pediatric pathologists for all included cases. Esophageal polyps were identified in 13 patients (9 M) from 9438 esophagogastroduodenoscopies (0.14%). Mean age of subjects was 9.2 years. Vomiting was the most common indication for endoscopy. Polyp location was at the gastroesophageal junction in 7 of the 13 cases. Most polyps were inflammatory (n = 7). Esophagitis was noted in 69% of those with esophageal polyps. Repeat endoscopies in six patients at a mean interval of 8 months noted persistence of polyps in all six patients. This paper is the first to characterize esophageal polyps in pediatrics. These polyps are rare in children and often are associated with esophagitis. Presenting complaints seem to vary by age. Polyps did not consistently change with either time or acid suppression. The optimal management strategy has yet to be defined and likely depends on the underlying pathophysiologic process.

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Endoscopic Removal of Inflammatory Esophagogastric Polyps in Children

Glassman,

Bostwick,

Godine

et al. 1991

J. pediatr. gastroenterol. nutr.

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SummaryTwo adolescent patients with inflammatory esophagogastric polyps (IEPs) are presented. In each case, the patients complained of chest pain and dysphagia. In one patient, there was no histological evidence of esophagitis in association with the IEPs. Their clinical course suggests that the presentation of IEPs in adolescents is indistinguishable from and may result in secondary gastroesophageal reflux and esophagitis. In each case, endoscopic polypectomy was utilized effectively as the mode of therapy.

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Gastroesophageal polyp diagnosed in an adolescent presenting with epigastric pain

Cited by 10 publications

References 5 publications

Effects of Proton Pump Inhibitors on Pediatric Inflammatory Esophagogastric Polyps

Effects of Proton Pump Inhibitors on Pediatric Inflammatory Esophagogastric Polyps

Esophageal polyps in pediatric patients undergoing routine diagnostic upper gastrointestinal endoscopy: a multicenter study

Endoscopic Removal of Inflammatory Esophagogastric Polyps in Children

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