Gastroenteritis eosinofílica: espectro clínico de una misma entidad

Higuera, Carlos de la Serna; Gómez, S. J. Rodríguez; Arribas, M.; Moreno, Juan A.; Villòria, Albert

doi:10.4321/s0212-71992002000700007

Cited by 4 publications

(6 citation statements)

References 9 publications

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“…Por este motivo deben obtenerse muestras tanto de zonas afectas como de zonas aparentemente normales, siendo las áreas preferentes el antro gástrico y el duodeno, por ser los sitios donde es mas común que se hallen estas anormalidades anatomopatológicas (5). Está indicada su realización de forma repetida en aquellos pacientes que presenten síntomas gastrointestinales inexplicables, eosinofilia periférica y biopsias previas negativas (20). La laparoscopia constituye actualmente un procedimiento alternativo eficaz en los casos de diagnóstico difícil no accesible por otras técnicas (21).…”

Section: Discussionunclassified

Gastroenteritis eosinofílica: a propósito de dos casos

García

Sanchez

Palomo

et al. 2004

An. Med. Interna (Madrid)

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Eosinophilic gastroenteritis is a rare condition characterized by eosinophilic infiltration or the different layers of the intestinal wall. Clinical symptoms depend of the site of eosinophilic infiltration and the layers involved. Usually characterized by peripheral eosinophilia. Definitive diagnosis is based on histopathological findings. We report two cases with excellent response to steroid therapy.

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Section: Discussionunclassified

Gastroenteritis eosinofílica: a propósito de dos casos

García

Sanchez

Palomo

et al. 2004

An. Med. Interna (Madrid)

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“…O diagnóstico de GE é realizado com uma alta suspeição clinica, demonstração histológica de infiltrado eosinofílico no TGI e afastamento de outras causas conhecidas para a eosinofilia periférica (SERNA HIGUERA et al, 2002), há de se observar que a distribuição irregular da doença, assim como a possível presença de formas sem infiltração da mucosa, podem gerar falsos negativos frequentes nas amostras de biópsia, acarretando possíveis subdiagnósticos, sendo recomendado múltiplas biopsias no esôfago, estômago e intestino, mesmo que a mucosa tenha um aspeto normal, para obtenção da confirmação diagnostica de gastroenterite eosinofílica (LIMA et al, 2012).…”

Section: Introductionunclassified

“…O prognóstico para os pacientes com gastroenterite eosinofílica é favorável mesmo que comumente haja exacerbação clinica, não há ocorrência de sequelas graves, que acarreta em diminuição da expectativa de vida (SERNA HIGUERA et al, 2002).…”

Section: Introductionunclassified

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Gastroenterite Eosinofílica Em Um Idoso: Relato De Caso

et al. 2018

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A Gastroenterite Eosinofílica (GE) é uma doença rara, crônica, de etiologia ainda desconhecida e com uma apresentação heterogênea, caracterizada por infiltração maciça de eosinófilos em, pelo menos, um dos segmentos do trato gastrointestinal. Seu quadro clinico é variável conforme o local e profundidade da infiltração, apresentando desde sintomas gastrointestinais comuns até doença oclusiva intestinal -o que torna a clínica inespecífica, exigindo alta suspeição, comprovação histológica e exclusão de várias patologias associadas a eosinofilia periférica para o fechamento do diagnóstico, sendo uma patologia possivelmente subdiagnósticada. Apresentamos o caso de um adulto com diarréia líquida e perda ponderal significativa, sem melhoras ao uso de medicamentos. Tratava-se de uma Gastroenterite Eosinofílica, patologia de exclusão, que respondeu ao uso de corticóide, estando assintomático até a descrição deste relato.Palavras chave: Diagnóstico; Eosinofilia; Gastroenterite; Trato Gastrointestinal. ABSTRACTEosinophilic Gastroenteritis in an elderly man: Case Report. Eosinophilic Gastroenteritis (GE) is a rare, chronic, disease of unknown etiology with a heterogeneous presentation, characterized by massive infiltration of eosinophils in at least one segment of the gastrointestinal tract. Its clinical condition varies according to the site and depth of the infiltration, ranging from common gastrointestinal symptoms to intestinal occlusive disease -which makes the clinic unspecific, requiring high suspicion, histological confirmation and exclusion of several pathologies associated with peripheral eosinophilia for the diagnosis closure, being a pathology possibly underdiagnosed. We present the case of an adult with liquid diarrhea and significant weight loss, with no improvement in medication use. It was an Eosinophilic Gastroenteritis, a pathology of exclusion, which responded to the use of corticosteroids, being asymptomatic up to the description of this report.

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“…The clinical presentation depends on the site and depth of eosinophilic infiltration [ 2 ]. Kaijser described the first case of this disease in 1937, and since then, approximately 300 cases have been reported in the literature [ 3 - 5 ].…”

Section: Introductionmentioning

confidence: 99%

Eosinophilic Gastroenteritis With Malabsorption, Acute Intestinal Obstruction, Ascites and Pleural Effusion: A Case Report and Review of Literature

Brasil¹

2013

Gastroenterology Research

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We report a case of a 49-year-old male patient with abdominal distension and diffuse stomach cramps associated with peripheral eosinophilia. Treatment for eosinophilic parasitosis was not effective. After a few weeks, the patient developed acute obstructive abdomen with ascites, which was atypically improved with the use of antispasmodics and analgesics. Upper digestive endoscopy, colonoscopy and histopathologic examination of the gastric and intestinal mucosa did not show any significant changes. Video laparoscopic biopsy of the mesenteric lymph node and peritoneum revealed a nonspecific chronic inflammatory process with intense diffuse tissue eosinophilia. Complementary tests revealed right-sided pleural effusion and increased serum immunoglobulin E levels, with altered D-xylose absorption test results. The patient was treated with a hypoallergenic diet and an oral corticosteroid; the symptoms resolved and the laboratory test results improved. Eosinophilic gastroenteritis is a rare inflammatory disease characterized by eosinophilic infiltration in the wall of the gastrointestinal tract. The clinical presentation varies according to the affected site and the depth and extent of digestive tract involvement. This case report, which presents the rare simultaneous involvement of the mucosal, muscular and serosal layers, aims to describe and discuss the clinical and therapeutic aspects of eosinophilic gastroenteritis as well as its progression.

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Gastroenteritis eosinofílica: espectro clínico de una misma entidad

Cited by 4 publications

References 9 publications

Gastroenteritis eosinofílica: a propósito de dos casos

Gastroenteritis eosinofílica: a propósito de dos casos

Gastroenterite Eosinofílica Em Um Idoso: Relato De Caso

Eosinophilic Gastroenteritis With Malabsorption, Acute Intestinal Obstruction, Ascites and Pleural Effusion: A Case Report and Review of Literature

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