Gastroduodenitis associated with ulcerative colitis

Hori, Keiichi; Ikeuchi, Hiroki; Nakano, Hiroki; Uchino, Motoi; Tomita, Toshihiko; Ohda, Yoshio; Hida, Nobuyuki; Matsumoto, Takayuki; Fukuda, Yoshihiro; Miwa, Hiroto

doi:10.1007/s00535-007-2143-8

Cited by 61 publications

(87 citation statements)

References 26 publications

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“…The presence of gastroduodenal lesions [5-10] and small bowel lesions [11-15] in UC has been reported in recent years, with an incidence of 4.7–7.6% [8, 9] for gastroduodenal lesions and 36–57% [13, 14] for small bowel lesions. Our study similarly found an incidence of 27.8% for small bowel lesions in UC, lending further support to the idea that such lesions are not uncommon in UC.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Small Bowel Lesions Using Capsule Endoscopy in Ulcerative Colitis and Crohn’s Disease: A Single-Center Retrospective Analysis

et al. 2018

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Background: Capsule endoscopy (CE) has allowed the characterization of small bowel lesions. However, small bowel lesions in ulcerative colitis (UC) have not been elucidated and no studies have compared between UC and Crohn’s disease (CD). Aim: The objective of this study was to investigate the small bowel lesions in UC, and to characterize UC lesions by comparison with CD. Methods: Subjects comprised 54 UC patients and 39 CD patients who underwent CE. We retrospectively investigated characteristics of small bowel lesions in UC. We also compared endoscopic findings and degree of inflammation between UC and CD. Results: The incidence of small bowel lesions in UC was 27.8%. The group with small bowel lesions exhibited higher endoscopic activity in the colon than without small bowel lesions (p = 0.002). Comparing small bowel lesions between UC and CD, significantly more ulcerative lesions, notched appearance, longitudinal tendency of lesions, and cobblestone appearance were seen in CD. The Lewis score was significantly higher in CD than UC in the second and third tertiles (205 ± 379 vs. 73 ± 223, p = 0.01; 358 ± 449 vs. 105 ± 333, p < 0.001). Conclusions: Small bowel lesions in UC were linked to colonic activity. UC and CD differ in terms of the morphology and distribution of small bowel lesions.

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Section: Discussionmentioning

confidence: 99%

Comparison of Small Bowel Lesions Using Capsule Endoscopy in Ulcerative Colitis and Crohn’s Disease: A Single-Center Retrospective Analysis

et al. 2018

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“…Gastroduodenal involvement is more frequent in young people (1,3), and is related with low doses of corticoids, recurrent pouchitis (7.4% of the cases) and more serious forms of presentation (active pancolitis, 6.2%) (1,2).…”

Section: Discussionmentioning

confidence: 99%

Ulcerative colitis with gastric and duodenal involvement

2017

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“…Fourth, the UC patients enrolled in this study were almost in remission and had only mild disease activity. It is unknown whether the disease activity of UC might be related to the incidence of gastroduodenitis associated with UC and backwash ileitis [32,33]. On the other hand, it has been reported that extraintestinal manifestations such as those related to the joints, skin and eyes are associated with UC activity in most cases [34].…”

Section: Discussionmentioning

confidence: 99%

Capsule-Endoscopic Findings of Ulcerative Colitis Patients

Higurashi

Endo²,

Yoneda³

et al. 2011

Digestion

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Background/Aims: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by diffuse mucosal inflammation, traditionally regarded as being limited to the colorectum. Although several gastroduodenal lesions have also been reported recently in cases of UC, in general, small-bowel lesions in UC are believed to be extremely rare. The aim of this study was to examine the small bowel by capsule endoscopy in patients with UC. Methods: The study was conducted in 23 well-documented UC patients and 23 control volunteers. The frequency of small-bowel lesions, the number of small-bowel lesions per patient and the capsule endoscopy score were comparatively evaluated between the two groups. Results: Of the 23 UC patients, 13 (57%) showed small-bowel lesions, and 8 (35%) had erosions. There were significant differences in the frequency of the small-bowel lesions (p < 0.001) and erosions (p = 0.009) between the two groups. The capsule endoscopy score was correlated with the UC disease activity index (r = 0.718, p < 0.001). Conclusions: This is the first capsule-endoscopic study conducted to examine the small-bowel involvement in UC patients as compared with the healthy volunteers. It was concluded that UC, a chronic inflammatory bowel disease, can also involve the small bowel.

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Gastroduodenitis associated with ulcerative colitis

Abstract: The high prevalence of GDUC suggests that the gut inflammatory reaction in UC may not be restricted to the large intestine. Administered steroids might conceal GDUC, and more aggressive UC such as active pancolitis may be related to the development of GDUC.

Cited by 61 publications

References 26 publications

Comparison of Small Bowel Lesions Using Capsule Endoscopy in Ulcerative Colitis and Crohn’s Disease: A Single-Center Retrospective Analysis

Comparison of Small Bowel Lesions Using Capsule Endoscopy in Ulcerative Colitis and Crohn’s Disease: A Single-Center Retrospective Analysis

Ulcerative colitis with gastric and duodenal involvement

Capsule-Endoscopic Findings of Ulcerative Colitis Patients

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