Gastroduodenal phytobezoar treated with Coca-Cola®

Rodicio, José L.; Bongera, Miguel; Abdel-Lah, O.; Hevia, Ignacio Meléndez; Alonso, Begoña Olmedilla; Herrero, M.; Martínez, Miguel; Vega, Ángeles; Ayala, José María Beltrán; Pozo, Faustino

doi:10.4321/s1130-01082012000200014

Cited by 10 publications

(4 citation statements)

References 4 publications

(4 reference statements)

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“…We identified 24 publications that included case reports with 1 up to 5 patients and one retrospective study with 17 patients . Patients' characteristics and outcome are shown in detail in Table S1.…”

Section: Resultsmentioning

confidence: 99%

Systematic review: Coca‐Cola can effectively dissolve gastric phytobezoars as a first‐line treatment

Ladas¹,

Kamberoglou²,

Karamanolis³

et al. 2012

Aliment Pharmacol Ther

162

127

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Section: Resultsmentioning

confidence: 99%

Systematic review: Coca‐Cola can effectively dissolve gastric phytobezoars as a first‐line treatment

Ladas¹,

Kamberoglou²,

Karamanolis³

et al. 2012

Aliment Pharmacol Ther

162

127

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“…In symptomatic patients, the dissolution or removal of the bezoars is usually performed; however, there is no consensus regarding the management of bezoars. To date, there have been several reports describing the clinical utility of administering Coca-Cola to dissolve phytobezoars (4,6,29,30). The first successful treatment outcomes achieved with Coca-Cola lavage were reported in 2002 by Ladas et al, who treated five gastric phytobezoar patients (4).…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

et al. 2014

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Objective To analyze the clinical characteristics of patients with gastrointestinal bezoars and their response to therapy. Patients We retrospectively reviewed the cases of 19 patients diagnosed with gastrointestinal bezoars at the Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences or one of 15 collaborating institutions between December 2004 and August 2013. We investigated the epidemiology and etiology of the gastrointestinal bezoars by determining the gender, age at diagnosis, medical history, symptoms, complications, modalities used for diagnosis, treatments, outcomes and bezoar location, color and contents. Results There were 17 patients with gastric bezoars and two patients with small intestinal bezoars. All patients were 62 years of age or older, except for one case of a trichobezoar in a 10-year-old patient. Some of the patients had a history of surgery of any part of the gastrointestinal tract (n=5) and/or diabetes mellitus (n=2). The two patients with small intestinal bezoars required surgical removal in order to relieve ileus. Approximately one-half of the patients with gastric bezoars had ulcerations in the stomach (9/17 patients, 52.9%) and/or gastrointestinal bleeding (8/17, 47.1%). Endoscopic fragmentation was performed in 10 patients, whereas bezoar dissolution was achieved with a gastroprokinetic agent (n=1) and without any treatment (n=3) in the remaining cases. Conclusion As previously reported, elderly individuals with a positive history of surgery and/or diabetes mellitus were observed in this bezoar patient series. Gastric ulcers and gastrointestinal bleeding were frequently observed. The majority of patients underwent endoscopic fragmentation, while spontaneous resolution of the gastric bezoar was observed in several cases.

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“…Although medical treatment is often complementary to endoscopy, there have been published cases where it was successful on its own [17, 23, 26]. The pharmacologic approach includes everything from diet measures and the use of prokinetics to the enzymatic dissolution of the bezoar with agents such as cellulose, which shows the best results with an effectiveness of 83–100% [30]. Conservative management involves endoscopy and gastric lavage; however, diospyrobezoars are resistant to drug treatment and are more resistant than other phytobezoars.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, the bicarbonate content and the CO 2 bubbles have mucolytic action. There are several publications describing the successful use of Coca-Cola TM in treating bezoars, in some cases after failure of endoscopic fragmentation and after failed dissolution by enzymatic drugs [30, 31]. However, it should be noted that the partial dissolution of bezoars located in the stomach can cause them to migrate to the small bowel, resulting in intestinal obstruction.…”

Section: Discussionmentioning

confidence: 99%

Diospyrobezoar as a Cause of Small Bowel Obstruction

Toledo

Rodrigues

et al. 2012

Case Rep Gastroenterol

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Phytobezoar, a concretion of indigestible fibers derived from ingested vegetables and fruits, is the most common type of bezoar. Diospyrobezoar is a subtype of phytobezoar formed after excessive intake of persimmons (Diospyros kaki). We report the case of a diabetic man with a 5-day history of abdominal pain after massive ingestion of persimmons who developed signs of complicated small bowel obstruction. The patient had a previous history of Billroth II hemigastrectomy associated with truncal vagotomy to treat a chronic duodenal ulcer 14 years earlier. Since intestinal obstruction was suspected, he underwent emergency laparotomy that revealed an ileal obstruction with small bowel perforation and local peritonitis due to a phytobezoar that was impacted 15 cm above the ileocecal valve. After segmental intestinal resection, the patient had a good recovery and was discharged on the 6th postoperative day. This report provides evidence that diospyrobezoar should be considered as a possible cause of small bowel obstruction in patients who have previously undergone gastric surgery.

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Gastroduodenal phytobezoar treated with Coca-Cola®

Cited by 10 publications

References 4 publications

Systematic review: Coca‐Cola can effectively dissolve gastric phytobezoars as a first‐line treatment

Systematic review: Coca‐Cola can effectively dissolve gastric phytobezoars as a first‐line treatment

Clinical Characteristics and Treatment Outcomes of Nineteen Japanese Patients with Gastrointestinal Bezoars

Diospyrobezoar as a Cause of Small Bowel Obstruction

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