Gastroduodenal Burkitt's lymphoma in an immunocompetent patient

Rodrigues‐Pinto, Eduardo; Gonçalves, Regina; Fonseca, Elsa; Macedo, Guilherme

doi:10.4321/s1130-01082013000900007

Cited by 1 publication

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“…Endoscopy is important to establish the diagnosis of GI BL by taking biopsies of the affected area and to define tumor extension and infiltration. Although there are no pathognomonic lesions, several endoscopic signs have been associated with BL in the stomach (submucosal nodules [ 13 ], single or multiple tumors with or without ulceration [ 14 ], diffuse ulceration of the stomach [ 15 ], and thickening of gastric folds [ 16 ]) and colon (polypoid masses [ 7 ] and partially obstructive heterogeneous non-ulcerated masses [ 5 ]). As there is no definitive test that establishes the diagnosis of BL, it is important to recognize that GI endoscopy is one of many tools used in combination with other imaging and histopathologic techniques to increase the diagnostic accuracy of this rare malignancy [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Burkitt’s Lymphoma of the Rectosigmoid and Stomach Presenting as Hematochezia

et al. 2016

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Patient: Female, 51Final Diagnosis: Burkitt’s lymphoma of the rectum and stomachSymptoms: HematocheziaMedication: —Clinical Procedure: EGD and colonoscopySpecialty: Gastroenterology and HepatologyObjective:Rare diseaseBackground:Burkitt’s lymphoma (BL) is an uncommon cause of non-Hodgkin lymphoma in adults and accounts for only 0.1–0.5% of all malignant tumors of the colon and rectum. Very few cases of rectosigmoid and stomach BL have been reported in adults.Case Report:A 51-year-old Hispanic woman presented with a 1-month history of hematochezia, associated with a foreign-body sensation in the rectum and 7 kg weight loss. Initial laboratory workup showed normocytic anemia and positive fecal occult blood. Computed tomography of the abdomen revealed an asymmetric appearance of the stomach and pylorus with nodularity of the mucosa and thickening of the posterior wall, and a 10.8-cm rectal mass. Esophagogastroduodenoscopy and colonoscopy were performed and biopsies of the stomach and rectum were obtained; histopathology demonstrated involvement by Burkitt’s lymphoma in the gastric body nodule and rectal mass. After 4 cycles of chemotherapy, a follow-up abdominal CT demonstrated complete resolution of the mural thickening of the rectum and no intra-abdominal lymphadenopathy.Conclusions:Our case illustrates the importance of considering BL in the extensive differential diagnosis of rectal bleeding, change in bowel habits, and other lower and upper GI symptoms, since the rapidly growing nature of this rare malignancy requires a prompt diagnosis and initiation of appropriate therapy.

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