This study aimed to establish the optimal diagnostic and treatment algorithm for the management of Gastric Fistula in the Chest (GFIC) after Sleeve Gastrectomy (SG) through a systematic review of published cases. A multi-database search was performed which produced 1182 results, of which twenty-six studies were included in this systematic review. The initial presentation included subphrenic collections, leaks, or (recurrent) pneumonia with associated symptoms such as persistent cough, fever and/or dyspnoea.Computed Tomography (CT) scan in combination with either Upper Gastrointestinal series (UGI) or an Esophagogastroduodenoscopy (EGD) was used to adequately diagnose the fistulas. Initial treatment was either with clips and/or clips and stents that were placed endoscopically. When unsuccessful in majority of the cases, the surgical treatment consisted in a total gastrectomy and Roux-en-Y esophagojejunostomy in a laparoscopic or open fashion.