Gastro-Splenic Fistula Related to Large B Cell Lymphoma

Abstract

We report a case of spontaneous gastrosplenic fistula in a 57 year old female who presented to the emergency department with abdominal pain and weight loss. From the physical examination, she had a palpable abdominal mass. A CT scan was performed and showed a mass involving the proximal greater curve of the stomach, infiltrating the spleen and pancreas. There was a 12 mm defect in the cardia of the stomach with gas entering the large mass but there was no free gas in the abdomen. The defect was a gastrosplenic fistula. A gastroscopic biopsy confirmed the diagnosis of diffuse large B cell lymphoma. Surgical removal of the mass was not feasible; therefore she was treated with RCHOP chemotherapy, achieving complete remission.

An Unusual Differential Diagnosis of Gastric Haemorrhage: A Rare Case of Gastrosplenic Fistula

“…Gastrosplenic fistula is a rare complication of gastric or splenic malignancies or more rarely of benign pathologies such as Crohn's disease, splenic abscess and trauma, melioidosis or sickle cell disease [1][2][3][4][5] . In neoplastic diseases it can occur spontaneously or after chemotherapy, radiation therapy or their combination.…”