Gastro-intestinal tuberculosis. A 10–year review

Bentley, Gail; Webster, John H.

doi:10.1002/bjs.1800540203

Cited by 40 publications

(14 citation statements)

References 18 publications

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“…In Rauf's (1984) series average age of the patients was 31.6 years and in Mahboob's (1995) series it was 26.5 years 6 . Bently et al showed that the average age among their patients was 63 years 7 . These patients were Britons.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological Study of Intestinal Tuberculosis & its Management

Islam

Rahman

Islam³

et al. 1970

TAJ: J of Teachers Assoc

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Intestinal tuberculosis is still a common abdominal problems in developing countries like us. Sixty cases of intestinal tuberculosis admitted in the surgical wards of Mymensingh Medical College Hospital over 2 years with different presentations have been studied here. All of them under went through surgical procedures for their management. The age range of the patients was 13 to 55 years and most commonly involved age group was 20-40 years. Male to female ratio was 1:1.4. 60% of the patients were in low socio-economic group and 20% of the patients had got the positive history of contact. 60% of the patients presented with chronic intestinal obstruction. The most commonly involved site was lleocaecal region in 51.6% of the patients. Right hemicolectomy with ileotransverse anastomosis was performed commonly 63.3% of the patients but limited resection and stricturoplasty are also safe and effective procedures.

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Section: Discussionmentioning

confidence: 99%

Clinicopathological Study of Intestinal Tuberculosis & its Management

Islam

Rahman

Islam³

et al. 1970

TAJ: J of Teachers Assoc

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“…Although these anticolon antibodies may arise due to cross-reactivity with Escherichia coli 014:K1 antigens (260), the documentation is rather weak. Circulating immune complexes are also observed in Crohn's disease (67,99,153 (20,41). Chemotherapy is only an adjunct to surgical intervention and is often not necessary (3,41).…”

Section: Epidemiologymentioning

confidence: 99%

“…The effect of placebo on maintaining clinical remission is even more striking. Of 20 patients achieving remission while on placebo (267), 15 (75%) remained well for at least 1 year. Of 11 patients followed for a second year, 7 (63%) remained in remission.…”

Section: Epidemiologymentioning

confidence: 99%

Crohn's disease and the mycobacterioses: a review and comparison of two disease entities

1989

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Crohn's disease is a chronic granulomatous ileocolitis, of unknown etiology, which generally affects the patient during the prime of life. Medical treatment is supportive at best, and patients afflicted with this disorder generally live with chronic pain, in and out of hospitals, throughout their lives. The disease bears the name of the investigator who convincingly distinguished this disease from intestinal tuberculosis in 1932. This distinction was not universally accepted, and the notion of a mycobacterial etiology has never been fully dismissed. Nevertheless, it was 46 years after the distinction of Crohn's disease and intestinal tuberculosis before research attempting to reassociate mycobacteria and Crohn's disease was published. Recently, there has been a surge of interest in the possible association of mycobacteria and Crohn's disease due largely to the isolation of genetically identical pathogenic Mycobacterium paratuberculosis from several patients with Crohn's disease in the United States, the Netherlands, Australia, and France. These pathogenic organisms have been isolated from only a few patients, and direct evidence for their involvement in the disease process is not clear; however, M. paratuberculosis is an obligate intracellular organism and strict pathogen, which strongly suggests some etiologic role. Immunologic evidence of a mycobacterial etiology, as assessed by humoral immune determinations, has been conflicting, but evaluation of the more relevant cellular immunity has not been performed. Data from histochemical searches for mycobacteria in Crohn's disease tissues have been equally conflicting, with acid-fast bacilli detected in 0 to 35% of patients. Animal model studies have demonstrated the pathogenic potential of isolates as well as elucidated the complexity of mycobacterial-intestinal interactions. Treatment of Crohn's disease patients with antimycobacterial agent has not been fully assessed, although case reports suggest efficacy. The similarities in the pathology, epidemiology, and chemotherapy of Crohn's disease and the mycobacterioses are discussed. The issue is fraught with controversy, and the data generated on the association of mycobacteria and Crohn's disease are in their infantile stages so that a general conclusion on the legitimacy of this association cannot be made. While no firm evidence clearly implicates mycobacteria as an etiologic agent of Crohn's disease, the notion is supported by suggestive and circumstantial evidence and a remarkable similarity of Crohn's disease to known mycobacterial diseases.

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“…Nevertheless, there are several reports of abdominal tuberculosis showing the lack of radiological evidence of pulmonary tuberculosis in 50% to 80% of cases [15].…”

Section: Discussionmentioning

confidence: 99%

Primary Gastric Tuberculosis: A Case Report

Al-Quorain

1992

Ann Saudi Med

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Gastro-intestinal tuberculosis. A 10–year review

Cited by 40 publications

References 18 publications

Clinicopathological Study of Intestinal Tuberculosis & its Management

Clinicopathological Study of Intestinal Tuberculosis & its Management

Crohn's disease and the mycobacterioses: a review and comparison of two disease entities

Primary Gastric Tuberculosis: A Case Report

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