Gastro-Intestinal Tract Cancers Following Bariatric Surgery: a Narrative Review

Ebrahimi, Reza; Kermansaravi, Mohammad; Khalaj, Alireza; Eghbali, Foolad; Mousavi, Ali; Pazouki, Abdolreza

doi:10.1007/s11695-019-04007-y

Cited by 12 publications

(15 citation statements)

References 86 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Corte axial en fase arterial de tomografía computada de abdomen y pelvis: Engrosamiento parietal asimétrico de cuerpo gástrico en curvatura menor. la pérdida de peso y a una disminución del estado proinflamatorio sostenido en pacientes obesos 1,30 . Por su parte, poco se sabe particularmente acerca de la relación de la CB con el desarrollo de cáncer gástrico, y aún falta evidencia para establecer una conexión con la aparición de adenocarcinoma gástrico 23,24,31 .…”

Section: Discussionunclassified

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Parada¹,

Tapia²,

Vidal³

2022

Rev. Cirugia

View full text Add to dashboard Cite

Introducción: La obesidad y el índice de masa corporal (IMC) actúan como factores de riesgo para diversas neoplasias, sin una clara relación con el cáncer gástrico no cardial. La cirugía bariátrica es el manejo más efectivo contra la obesidad. La incidencia de cáncer gástrico posterior a la gastrectomía vertical es aún incierta. El primer caso de cáncer gástrico, 4 años posterior a una gastrectomía vertical, se publicó en 2014, y hasta la fecha se han descrito 11 casos en la literatura.Caso clínico: Masculino de 52 años, con antecedente de gastrectomía vertical, presenta cuadro clínico, endoscópico e histopatológico compatible con adenocarcinoma de cuerpo gástrico 5 años posterior a cirugía bariátrica. Recibe tratamiento neoadyuvante con quimioterapia esquema FLOT 6 ciclos, luego gastrectomía total oncológica laparoscópica con disección ganglionar D2 y adyuvancia con esquema FOLFOX 6 ciclos. Estudio histopatológico resulta adenocarcinoma pobremente diferenciado con 90% de regresión tumoral, sin metástasis ganglionar en lo extraído (pT1bN0M0). Seguimiento por 6 meses sin signos clínicos e imagenológicos de recidiva tumoral.Discusión: Existiría una relación directa entre el IMC y cáncer de unión gastroesofágica, la que no ha sido demostrada para cáncer gástrico no cardial. El estudio con endoscopía digestiva alta previo a cirugía bariátrica no está estandarizado, sin embargo, es recomendable realizarlo. La cirugía bariátrica podría disminuir el riesgo de ciertas neoplasias, mientras que la incidencia de cáncer gástrico posterior a dicha cirugía aún no está bien definida. Es recomendable realizar seguimiento endoscópico a los pacientes postoperados de gastrectomía vertical, más aun en sintomáticos.

show abstract

Section: Discussionunclassified

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Parada¹,

Tapia²,

Vidal³

2022

Rev. Cirugia

View full text Add to dashboard Cite

show abstract

“…Obesity is known to increase esophageal cancer incidence [23]; however, bariatric surgery reduces the risk of obesityrelated malignancies [24]. The incidence of esophageal cancer after bariatric surgery had not been confirmed to date.…”

Section: Global Esophageal Cancer Estimates After Bariatric Surgerymentioning

confidence: 99%

Esophageal Cancer After Bariatric Surgery: Increasing Prevalence and Treatment Strategies

et al. 2021

View full text Add to dashboard Cite

Purpose The number of bariatric procedures has increased exponentially over the last 20 years. On the background of ever-increasing incidence of esophageal malignancies, the altered anatomy after bariatric surgery poses challenges in treatment of these cancers. In this study, an epidemiological estimate is presented for the future magnitude of this problem and treatment options are described in a retrospective multicenter cohort. Methods The number of bariatric procedures, esophageal cancer incidence, and mortality rates of the general population were used for epidemiological estimates. A retrospective multicenter cohort was composed; patients were treated in three large oncological centers with a high upper gastrointestinal cancer caseload. Consecutive patients with preceding bariatric surgery who developed esophageal cancer between 2014 and 2019 were included. Results Approximately 3200 out of 6.4 million post bariatric surgery patients are estimated to have developed esophageal cancer between 1998 and 2018 worldwide. In a multicenter cohort, 15 patients with esophageal cancer or Barrett’s esophagus and preceding bariatric surgery were identified. The majority of patients had a history of Roux-en-Y gastric bypass (46.7%) and had an adenocarcinoma of the distal esophagus (60%). Seven patients received curative surgical treatment, five of whom are still alive at last follow-up (median follow-up 2 years, no loss to follow-up). Conclusion Based on worldwide data, esophageal cancer development following bariatric surgery has increased over the past decades. Treatment of patients with esophageal cancer after bariatric surgery is challenging and requires a highly individualized approach in which optimal treatment and anatomical limitations are carefully balanced. Graphical abstract

show abstract

“…Most esophageal adenocarcinomas are due to gastroesophageal reflux disease and Barrett's esophagus (BE) [1] , [2] , [3] , [4] , [8] , [9] . By worsening a gastroesophageal reflux, restrictive procedures such as laparoscopic adjustable gastric banding (LAGB) or sleeve gastrectomy (SG) can create or exacerbate a BE [2] , [7] , [8] , [10] , which can evolve more rapidly to dysplasia leading to an esophageal adenocarcinoma (ADK) [8] , [10] .…”

Section: Introductionmentioning

confidence: 99%

Gastro-Intestinal Tract Cancers Following Bariatric Surgery: a Narrative Review

Cited by 12 publications

References 86 publications

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Cáncer gástrico y cirugía bariátrica: a propósito de un caso

Esophageal Cancer After Bariatric Surgery: Increasing Prevalence and Treatment Strategies

Esophagectomy for Barrett's adenocarcinoma after multiple bariatric surgeries: A case report

Contact Info

Product

Resources

About