Gastro-esophageal Reflux Disease in Lebanese Adults: Effects on Quality of Life and Correlates

Awada, S.; Rachidi, Samar; Al‐Hajje, Amal; Zeidan, Rouba Karen; Kansou, N. Bou; Abboud, Camille N.; Bawab, Wafaa; Salameh, Pascale

doi:10.5567/pharmacologia.2014.339.350

Cited by 3 publications

(4 citation statements)

References 41 publications

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“…Males presented a higher mean RQS score than females, in contrast to the work of Hill et al (2021). A negative correlation was found between QoL and age as well as the total number of typical and atypical symptoms for each patient, similarly shown in a study of Awada et al (2014). Additional multivariate analysis is needed to better understand the impact of demographic and clinical characteristics of patients with GERD in their QoL.…”

Section: Discussionmentioning

confidence: 83%

“…In all cases deemed necessary, nonparametric tests and exact tests or Monte Carlo simulation (10,000 samples) were applied. The psychometric properties of the RQS, its validity and reliability, were assessed according to recommendations in the field of psychometrics (Field, 2013; Galanis, 2013) and relevant studies (Awada et al, 2014). The IBM Statistics v.20.0 was mainly used to analyze the data.…”

Section: Methodsmentioning

confidence: 99%

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Reflux-Qual-Short-Form Questionnaire: Translation and Validation of the Greek Version

Georganta

Koreli

Mantoudi

et al. 2022

Gastroenterology Nursing

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The aim of this study was the translation and validation of the Reflux-Qual Short-Form (RQS), a quality of life questionnaire in a Greek sample of 148 individuals with gastroesophageal reflux disease (GERD). This tool through eight items explores the effects of GERD in five dimensions of quality of life: daily activity, well-being, psychological impact, sleep, and eating. Exploratory factor analysis yielded a one-factor scale for the Greek-translated version. Internal consistency reliability of the questionnaire was deemed very satisfactory based on Cronbach's alpha coefficient, which was equal to 0.816. Split-half reliability was evaluated as an additional measure of internal consistency. The test–retest reliability analysis revealed a good stability after a 1-month interval. Construct validity was measured by the correlation level between each item and the adjusted global score, resulting in an acceptable level of convergence between the items. Concurrent validity was confirmed using the 36-Item Short Form Health Survey (SF-36) as a reference scale. This study indicates that RQS Questionnaire is a short, simple, reliable, and valid tool that can be used to assess quality of life in Greek individuals with GERD.

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Section: Discussionmentioning

confidence: 83%

Section: Methodsmentioning

confidence: 99%

Reflux-Qual-Short-Form Questionnaire: Translation and Validation of the Greek Version

Georganta

Koreli

Mantoudi

et al. 2022

Gastroenterology Nursing

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“…The principal hypothesis linking GERD and obesity to EAC is that chronic GERD, which is exacerbated by abdominal obesity, initiates the metaplasia-dysplasia-carcinoma sequence, and increase the risk of EAC through BE [ 12 ]. The prevalence of GERD was reported to be 24.8% among a representative sample of Lebanese in 2012 [ 13 ]. Likewise, obesity rate is increasing and reached 23.1% in 2014 as reported by the WHO.…”

Section: Discussionmentioning

confidence: 99%

Esophageal cancer: a twenty-four-year experience at a tertiary care center with an evaluation of the prognostic significance of the neutrophil-lymphocyte ratio

Mahmoud,

Hassoun,

Kerbage

et al. 2024

BMC Gastroenterol

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Background A high neutrophil-lymphocyte ratio (NLR) may be associated with worse survival in esophageal cancer (EC). Our aims were to describe the demographic and clinical data of EC in a tertiary referral center in Lebanon and to determine the prognostic value of NLR. Methods A retrospective cohort study based on chart review of patients diagnosed with EC was conducted at the American University of Beirut Medical Center (AUBMC). The demographic characteristics, clinical presentation and outcomes were described and compared between squamous cell carcinomas (ESCC) and adenocarcinomas (EAC). Data about esophageal cancer incidence were obtained from the National Cancer Registry, the Ministry of Public Health and GLOBOCAN 2020. Cox regression analysis was performed to determine whether the NLR is an independent predictor of survival, using variables based on clinical knowledge and previously established data. Results 110 patients were diagnosed with EC, which was the least common among other gastrointestinal malignancies. Our follow up rates reached 86.4%. The median survival was 9 months (IQR 3–25.5.) and was comparable between ESCC (median of 7 months, IQR 2–25) and EAC (median of 9 months, IQR 3–26.3), p = 0.803. Advanced stage was associated with a worse prognosis (p = 0.037). The mean NLR(±SD) was 5.20 ± 6.8, with no significant difference between EAC and ESCC (4.5 ± 3.4 vs. 5.9 ± 9.2, p = 0.420) or between early or advanced stages (5.4 ± 8.1 vs. 4.7 ± 6.8, p = 0.732). The area under the curve for the NLR was 0.560 (95% CI: 0.374–0.746, p = 0.488). After adjusting for age, gender, TNM staging and grading, cox regression analysis showed that an increased NLR was a significant predictor of mortality, with an adjusted hazard ratio of 1.095 (p = 0.011). Conclusion EC is quite uncommon in Lebanon despite a high prevalence of smoking and obesity. Advanced stage and high NLR were associated with a negative prognostic value.

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“…Identycznie sytuacja przedstawiała się z częstością występowania objawów. Chorzy skarżyli się przeważnie na takie objawy, jak: zgaga, ból i trudności podczas połykania oraz zarzucanie treści pokarmowej z żołądka do przełyku [13].…”

Section: Objawy Występujące W Przebiegu Choroby Refluksowej Przełykuunclassified

The Impact of Clinical Symptoms and the Type of Treatment on Quality of Life in Patients with Gastroesophageal Reflux Disease – Review of the Literature

Bąk¹,

Dyrla²,

Gil³

2015

Piel. Zdr. Publ.

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A -koncepcja i projekt badania; B -gromadzenie i/lub zestawianie danych; C -analiza i interpretacja danych; D -napisanie artykułu; E -krytyczne zrecenzowanie artykułu; F -zatwierdzenie ostatecznej wersji artykułu StreszczenieChoroba refluksowa przełyku jako schorzenie przewlekłe stanowi poważny problem zarówno dla pacjentów, jak i ich najbliższego otoczenia. Prowadzi do obniżenia jakości życia, co w rezultacie może być przyczyną negatywnych zachowań i emocji. Jednym z podstawowych elementów opieki medycznej sprawowanej nad przewlekle chorym jest zapewnienie optymalnej jakości życia. Ocena jakości życia pacjenta mającego chorobę refluksową przełyku, a także rozpoznanie czynników wpływających na jakość życia takiej osoby pozwalają lepiej zrozumieć, jak schorzenie wpływa na codzienne funkcjonowanie. Występowanie objawów choroby refluksowej oraz rodzaj stosowanego leczenia znacząco wpływają na poziom jakości życia chorych. Dzięki skutecznemu leczeniu zmniejszają się bądź całkowicie ustępują objawy choroby, poprawia się więc jakość życia chorego. Dzięki opanowaniu ciężkości i czę-stości objawów, odpowiednio dobranemu leczeniu pacjenci mający chorobę refluksową przełyku mogą normalnie funkcjonować w życiu codziennym, a ich poziom jakości życia nieznacznie odbiega od jakości życia osób zdrowych (Piel. Zdr. Publ. 2015, 5, 3, 441-448).Słowa kluczowe: choroba refluksowa przełyku, jakość życia, zgaga, inhibitory pompy protonowej. AbstractGastroesophageal reflux disease is one of the most common gastrointestinal disorders. This chronic disease is a serious problem not only for patients but also for their immediate environment, because it leads to disability of the patient, may be the cause of negative behaviors and emotions, in effect reducing quality of life. Effective treatment of GERD is necessary to provide symptomatic relief and, in turn, to improve the patient's health-related quality of life. Symptoms of gastroesophageal reflux disease and the type of treatment have a substantial impact on health-related quality of life in patients with GERD. Thanks to controlling the symptoms and a proper type of treatment, people with GERD can lead normal lives and their quality of life is similar to quality of life in the general population (Piel. Zdr. Publ. 2015, 5, 3, 441-448).

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Gastro-esophageal Reflux Disease in Lebanese Adults: Effects on Quality of Life and Correlates

Cited by 3 publications

References 41 publications

Reflux-Qual-Short-Form Questionnaire: Translation and Validation of the Greek Version

Reflux-Qual-Short-Form Questionnaire: Translation and Validation of the Greek Version

Esophageal cancer: a twenty-four-year experience at a tertiary care center with an evaluation of the prognostic significance of the neutrophil-lymphocyte ratio

The Impact of Clinical Symptoms and the Type of Treatment on Quality of Life in Patients with Gastroesophageal Reflux Disease – Review of the Literature

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