Gastro esophageal reflux disease (GERD) prevalence and related risk factors in north of Iran

Rabiee, Behnam; Motamed, Nima; Hosseini, Vahid; Hemasi, Gholam Reza; Maadi, Mansooreh; Zamani, Farhad

doi:10.1007/s10388-016-0536-6

Cited by 4 publications

(3 citation statements)

References 26 publications

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“…Although the findings on this matter are inconsistent, several studies showed direct relationship of GERD with smoking. 23,24 In the current study GERD was found to be more common in individuals who smoked with odds ratio of 6.25. In the current study, 79.4% participants reported improvement in the severity of GERD with elevating the head of the bed during sleep.…”

Section: Discussionsupporting

confidence: 49%

Effects of Life style factors on the symptoms of gastro esophageal reflux disease: A cross sectional study in a Pakistani population

Ahmed¹,

Jamil

Shaikh

et al. 2019

Pak J Med Sci

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Background & Objective: Gastro esophageal reflux disease (GERD) broadly includes the whole spectrum of reflux disease symptoms like heartburn or acid regurgitation to endoscopic, reflux esophagitis or Barrett’s esophagus. Our aim therefore was to study the association between Gastroesophageal reflux disease symptoms and various lifestyle factors. Methods: A descriptive cross-sectional study was carried out in the outpatient department of Darul Sehat Hospital, Zubaida Medical Center and Liaquat National Hospital & Medical College, Karachi, Pakistan from January 2018 to October 2018. The selected candidates were asked to fill a validated GERD questionnaire and they were also asked about their lifestyle factors. Odds ratio and their 95% confidence interval were estimated using binary logistic regression with GERD symptoms as the study outcome. Results: A total of 2000 respondents completed the questionnaire. 69.3% gastroesophageal reflux disease cases were found in participants above 35 years of age while 56.9% subjects were male. The most common lifestyle factors associated with GERD were less exercise time (90.9%) (OR, 6.47; 95% CI, 4.91-8.53), 78.3% participants had habit of eating midnight snacks (OR, 5.08; 95% CI, 4.03-6.40), 87.3% participants reported less interval between dinner and sleep (OR, 6.98; 95% CI, 5.36-9.08). The most important factor relieving GERD symptoms was raising the head of bed during sleep (79.4%) while 43.3% subjects with the habit of post dinner walk reported fewer symptoms of GERD. Conclusion: Lifestyle factors particularly less physical activity, late evening meals, inadequate sleep, smoking and post dinner lying were found to be associated with GERD symptoms. doi: https://doi.org/10.12669/pjms.36.2.1371 How to cite this:Ahmed S, Jamil S, Shaikh H, Abbasi M. Effects of Life style factors on the symptoms of gastro esophageal reflux disease: A cross sectional study in a Pakistani population. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.1371 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionsupporting

confidence: 49%

Effects of Life style factors on the symptoms of gastro esophageal reflux disease: A cross sectional study in a Pakistani population

Ahmed¹,

Jamil

Shaikh

et al. 2019

Pak J Med Sci

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“…It's widely believed that lifestyle and dietary habits affect the occurrence of GERD. Studies [35] have shown that smoking and drinking could result in LES pressure decline and triggering or aggravating GERD symptoms. In order to clarify the differences in lifestyle and dietary habits in RGERD patients with and without NCCP, 12 life exposure factors were counted in the study.…”

Section: Discussionmentioning

confidence: 99%

High resolution esophageal manometry and life exposure factors in non-cardiac chest pain patients with refractory gastroesophageal reflux disease

Lyu

Zhang

et al. 2019

Preprint

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Background: Refractory gastroesophageal reflux disease (RGERD) is defined by the presence of troublesome GERD symptoms despite proton pump inhibitors (PPIs) treatments for 8-12 weeks. Non-cardiac chest pain (NCCP) is the most common atypical presentations. This study was aimed at clarifying the features of High Resolution Esophageal Manometry (HREM) and life exposure factors of NCCP in RGERD patients for guiding further therapeutic strategies. Methods: 83 RGERD patients were enrolled, in which 44 patients afflicted with NCCP as P group and 39 patients without NCCP as NP group. According to the endoscopy results, P group was further divided into reflux esophagitis group (RE group), non-erosive reflux disease group (NERD group) and Barrett’s esophagus group (BE group). HREM was performed to assess esophageal motility. Diverse questionnaires were conducted to evaluate severity of symptoms, quality of life, risk factors, degrees of anxiety and depression and so on. Results: a)Average resting pressures of the lower esophageal sphincter (LES), residual pressures of the LES and the esophageal distal contractile integral (DCI) score in P group were significantly lower than those in NP group (p<0.05). b)Average resting pressures of the upper esophageal sphincter (UES), residual pressures of the UES, lengths of the LES and the UES showed no difference between the two groups (p>0.05). c)Compared with NP group, the patients in P group had higher exposure to alcohol, coffee, sweets, overeating and stress (p<0.05). d)Anxiety and depression status of patients in P group were remarkably severer than those in NP group (p<0.05). e)The pain intensity in RE group and BE group was higher than NERD group (P<0.05), while there was no difference between RE group and BE group (P>0.05). Conclusions: Esophageal motility related anti-reflux barriers are much weaker in the RGERD patients with NCCP than those without NCCP, which mainly presents as the much lower average resting and residual pressures of the LES and DCI. Alcohol, coffee, sweets, overeating, stress, anxiety and depression are risk factors of RGERD-related NCCP. It’s suggested that the recovery of anti-reflux barriers and the avoidance of risk factors may be essential therapeutic strategies for improving the curative effect.

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“…Risk factors of GERD included: use of alcohol, hiatus hernia, obesity, pregnancy, scleroderma and smoking (11,12). In the current study, the most recognized risk factors of GERD were smoking (81.2%), alcohol (80.2%), obesity (76.2%), hiatus hernia (73.8%) and pregnancy (64.9%).…”

Section: Discussionmentioning

confidence: 99%

Assessment of the Knowledge of Gastroesophageal Reflux Disease among the Saudi Population of Altaif City

Taha

Sahaki²,

Maimsh

et al. 2018

Egyptian Journal of Hospital Medicine

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Background: gastroesophageal reflux disease (GERD) ranks as one of the most common gastrointestinal disorders. Up to this date, no studies examined the level of health knowledge of Saudi population about GERD. Aim of the study: this study aimed to assess knowledge about GERD signs, symptoms and risk factors in Saudi residents of Altaif City. Methods: this minimal knowledge questionnaire that was distributed among the general public in Altaif City, Saudi Arabia. The questionnaire consisted of two sections: section 1 included personal data and section 2 explored the awareness and knowledge about the most common symptoms and risk factors of GERD. Only questionnaires without missing data were subjected to statistical analysis. Results: respondents who answered all the questions correctly represented 7.4%, while those who answered all wrongly were 1.5%. The mean proportion of minimal medical knowledge (MMK) score was 64.66%. Respondents with higher education (p < 0.001), medical background (p = 0.004) and health knowledge derived from books (p = 0.001) achieved the highest total scores. Sex, residence, marital status, and past/family history of GERD seemed not to affect the mean MMK scores (p = 0.277, 0.234, 0.970, 0.873 and 0.085 respectively). Conclusion: some symptoms (Globus sensation, dysphagia and odynophagia) and risk factors (Scleroderma and asthma) for GERD remained unknown to nearly half the participants. We recommend providing health information concerning GERD on the Internet or to prepare booklets to be distributed through the health care facilities.

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Gastro esophageal reflux disease (GERD) prevalence and related risk factors in north of Iran

Cited by 4 publications

References 26 publications

Effects of Life style factors on the symptoms of gastro esophageal reflux disease: A cross sectional study in a Pakistani population

Effects of Life style factors on the symptoms of gastro esophageal reflux disease: A cross sectional study in a Pakistani population

High resolution esophageal manometry and life exposure factors in non-cardiac chest pain patients with refractory gastroesophageal reflux disease

Assessment of the Knowledge of Gastroesophageal Reflux Disease among the Saudi Population of Altaif City

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