Gastric volume changes in response to a meal: Validation of magnetic resonance imaging versus the barostat

Abstract

Purpose: To determine the accuracy of magnetic resonance imaging (MRI) volume scans: 1) to measure known meal volumes in vitro, and 2) to compare volume changes in response to a meal measured with the barostat with those measured with MRI in vivo.Materials and Methods: Polyethylene bags were filled with known volumes and MRI volume scans were performed to determine the accuracy of the volume measurements. Barostat measurements and MRI volume scans were performed simultaneously in 14 healthy subjects before and up to 90 minutes after ingestion of a liquid meal.Results: In vitro MRI-determined volumes showed an excellent linear relationship (r ¼ 0.995, P < 0.001) with actual meal volumes. Although fasting gastric volume, postprandial gastric volume, and relaxation volume measured with MRI were significantly larger compared to volumes measured with the barostat, volumes determined with both techniques showed excellent correlation.

Evaluation of Gastric Volumes: Comparison of 3-D Ultrasound and Magnetic Resonance Imaging

“…To evaluate the novel matrix method for gastric volume measurements, we compared 3-D US to dynamic MRI in healthy volunteers. Dynamic MRI is a wellestablished, validated, non-invasive and radioactive-free imaging technique for gastric volumes and motility (de Zwart et al 2002;de Zwart et al 2007;Haans et al 2011;Schwizer et al 2002;Sheybani et al, 2015).…”

“…Currently, barostat is still considered the gold standard to determine smooth muscle relaxation of the proximal stomach. However, dynamic MRI has proved to be a reliable alternative and has been validated against barostat (Haans et al 2011). Dynamic MRI is a non-invasive technique that does not expose patients to ionizing radiation, as is the case with SPECT.…”

Validation of a Novel 3‐Dimensional Sonographic Method for Assessing Gastric Accommodation in Healthy Adults

“…As opposed to the barostat, the novel method is noninvasive and allows visualization of the distal stomach. Since intubation and the placement of an inflatable bag in the proximal stomach are no longer required with 3D sonography, the physiologic gastric function will not be influenced by the test itself, as is the case with the barostat 2 , 4 , 5 . Compared to SPECT and MRI, 3D sonography is radiation free, and patients can sit in an upward‐positioned chair, instead of lying down for MRI or SPECT acquisition.…”

“…The barostat method is an invasive technique requiring intubation of a catheter with an inflatable bag attached to its distal end. This inflatable bag is capable of measuring stomach wall pressure and volume changes in the response to the proximal stomach stimuli 4 . As a result of this invasive feature, the barostat cannot be used in children.…”