Gastric ulcer penetrating to liver diagnosed by endoscopic biopsy

Abstract

Liver penetration is a rare but serious complication of peptic ulcer disease. Usually the diagnosis is made by operation or autopsy. Clinical and laboratory data were no specific. A 64-year-old man was admitted with upper gastrointestinal bleeding. Hepatic penetration was diagnosed as the cause of bleeding. Endoscopy showed a large gastric ulcer with a pseudotumoral mass protruding from the ulcer bed. Definitive diagnosis was established by endoscopic biopsies of the ulcer base.

Hepatic penetration by stomal ulcer: rare complication of a peptic ulcer

“…Most cases of ulcers penetrating the liver have been treated by surgical procedures [1,2]. In addition to the present report, there have been two other recent case reports that have demonstrated the effectiveness of medical treatments such as H2 blockers and PPIs [3,4].…”

Bile Ductular Proliferation in the Gastric Wall after Gastric Ulcer Penetration into the Liver

“…The hepatic-related complications of a perforated gastric ulcer are liver abscess, upper gastrointestinal hemorrhage, subcap- sular liver abscess, 6 and liver rupture. Kayacetin and Kayacetin 7 reported one case and reviewed 13 others of liver penetration by a peptic ulcer. A diagnosis was made in all cases by the presence of liver tissue on histological examinations of endoscopic biopsies, and males predominated (78.6%).…”

Right hepatic artery injury: an unusual complication of penetrated duodenal ulcer disease

“…However, in posterior dudodenal ulcer penetration, the most affected artery is the gastroduodenal artery. 8 In the world literature, there are only about 30 reported cases of peptic ulcers penetrated to the liver. All reported cases have manifested with gastrointestinal bleeding.…”

“…Between gastric ulcers and duodenal ulcers, the latter has been most frequently reported to penetrate the liver. 8 Penetration to the liver can lead to 4 other complications: pain, formation of liver abscesses, obstruction of the outflow tract or bleeding of the upper gastrointestinal tract. The organ most frequently penetrated is the pancreas, usually by antral or duodenal ulcers.…”