Gastric tuberculosis mimicking submucosal tumor: a case series

Zhu, Rong; Zhou, Yuankun; Wang, Haibo; Di, Lianjun; Zhao, Kui; Tuo, Biguang; Wu, Huichao

doi:10.1186/s12876-020-1175-x

Cited by 18 publications

(13 citation statements)

References 12 publications

(13 reference statements)

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“…Ultrasound-guided fine needle aspiration, EUS-guided Tru-Cut biopsy, and EUS-guided fine needle biopsy can aid in the diagnosis of TB because the lesions are often located in the submucosa; however, the diagnostic accuracy of biopsy in diagnosing gastric TB is low. 13 Polymerase chain reaction (PCR) of gastric aspirates has been used in the diagnosis of gastric TB, but the specificity is only approximately 85%. 14 Preoperatively in our patient, we considered that the mass in the gastric fundus was likely a stromal tumor according to the patient’s medical history and physical and auxiliary examination findings.…”

Section: Discussionmentioning

confidence: 99%

A rare case of gastric fundus tuberculosis with nonspecific abdominal pain

Yan

Lei

et al. 2021

J Int Med Res

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A 53-year-old patient who experienced recurring upper abdominal pain and discomfort for 4 years was admitted to our hospital. Gastroscopy was performed to identify the location of the pain and evaluate the characteristics of a mass in the abdomen. Endoscopic ultrasonography (EUS) and abdominal computed tomography (CT) revealed a space-occupying lesion in the gastric fundus, suggestive of a submucosal tumor and highly likely of stromal origin. Surgical resection of the lesion was performed for identification; however, postoperative histopathological examination of the lesion revealed gastric fundus tuberculosis (TB). Gastric TB is relatively rare; therefore, clinicians should be highly suspicious of patients with abdominal symptoms from regions with a high incidence of TB to prevent treatment delay caused by misdiagnosis.

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Section: Discussionmentioning

confidence: 99%

A rare case of gastric fundus tuberculosis with nonspecific abdominal pain

Yan

Lei

et al. 2021

J Int Med Res

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“…[ 64 ] GDTB may present as submucosal gastric tumors with non-specific abdominal pain and distention, but rarely as fistulas to surrounding viscera and peritonitis due to perforation. [ 65 66 67 68 ]…”

Section: Clinical Featuresmentioning

confidence: 99%

Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment

Alzanbagi¹,

Shariff²

2021

Saudi J Gastroenterol

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Tuberculosis (TB) once considered a disease of the developing world is infrequent in the developing world too. Its worldwide prevalence with a huge impact on the healthcare system both in economic and health terms has prompted the World Health Organization to make it a top priority infectious disease. Tuberculous infection of the pulmonary system is the most common form of this disease, however, extrapulmonary TB is being increasingly recognized and more often seen in immunocompromised situations. Gastrointestinal TB is a leading extrapulmonary TB manifestation that can defy diagnosis. Overlap of symptoms with other gastrointestinal diseases and limited accuracy of diagnostic tests demands more awareness of this disease. Untreated gastrointestinal TB can cause significant morbidity leading to prolonged hospitalization and surgery. Prompt diagnosis with early initiation of therapy can avoid this. This timely review discusses the epidemiology, risk factors, pathogenesis, clinical presentation, current diagnostic tools and therapy.

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“…Some of the above EUS features have been reported in the literature (such as heterogeneous or homogeneous hypoechoic masses, interruption of the esophageal adventitia, and enlarged mediastinal lymph nodes [13,14]). Of the four features, the fourth feature is especially important because it suggests that tuberculosis of the paraesophageal lymph nodes spread directly to the esophagus [15].…”

Section: Discussionmentioning

confidence: 99%

EUS in the diagnosis of pathologically undiagnosed esophageal tuberculosis

et al. 2020

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Background: Esophageal tuberculosis (ET) is relatively rare, and the diagnosis is challenging. The aim of this study was to evaluate the clinical features of ET and highlight the role of endoscopic ultrasonography (EUS) in the diagnosis of pathologically undiagnosed ET. Methods: We retrospectively analysed the clinical features, radiological performances, conventional endoscopic appearances, EUS features, treatment and outcomes of pathologically undiagnosed ET between January 2011 and December 2018. All 9 patients failed to be diagnosed by at least two repeated biopsies (such as routine biopsy, multipoint or deep biopsy, and even or EUS-guided fine-needle aspiration (EUS-FNA)). Results: Nine patients (66.7% female) with a mean age of 45 years (range 29-59) complained of retrosternal pain or discomfort, or (and) dysphagia. Esophagoscopy demonstrated protruding lesions in the mucosa with central ulcers or erosion in five patients, submucosal bulges with smooth surfaces in one patient, submucosal bulges with diverticula in one patient, ulcers with suspicious fistula formation in one patient, and multiple ulcers in one patient. None of the patients received confirmed histopathological or bacteriological diagnoses by repeated biopsies. However, they were first suspected to have ET based on EUS examination. Because EUS found some characteristic ultrasonographic changes, which were very helpful for the diagnosis of ET when combined with clinical manifestations, the patients subsequently received diagnostic antituberculosis therapy. Finally, the patients recovered or improved with follow-up times ranging from 3 to 10 months. Conclusions: EUS could help in the diagnosis of ET on basis of EUS features like poorly defined esophageal wall structure, enlarged paraesophageal or mediastinal lymph nodes, hypoechoic lesions of esophageal wall that are linked to the enlarged paraesophageal lymph nodes. However all attempts should be made to obtain histological or microbiological diagnosis.

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Gastric tuberculosis mimicking submucosal tumor: a case series

Cited by 18 publications

References 12 publications

A rare case of gastric fundus tuberculosis with nonspecific abdominal pain

A rare case of gastric fundus tuberculosis with nonspecific abdominal pain

Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment

EUS in the diagnosis of pathologically undiagnosed esophageal tuberculosis

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