Gastric secretory derangement in Menetrier's disease

Charles, René; Moss, Arthur J.; Kunz, Werner; Segal, Harry L.

doi:10.1007/bf02232660

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2006

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Cited by 16 publications

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“…The patient described may represent a case of the rare polypoid form of Me´ne´trie`rs disease. Thus, the patient may be anacidic, 3 owing to escape of interstitial fluid to the gastric lumen. The prominent folds in the oxyntic area and cystic structures in the mucosa are typical for Me´ne´trie`rs disease.…”

Section: To the Editormentioning

confidence: 98%

“…The prominent folds in the oxyntic area and cystic structures in the mucosa are typical for Me´ne´trie`rs disease. 3 Secondary to anacidity, hypergastrinemia develops stimulating the enterochromaffine like (ECL) cell to histamine release and to proliferation, 2 subsequently leading to parietal cell stimulation. 7 Long-term overstimulation of parietal cells may lead to parietal cell degeneration as shown in transgenic hypergastrinemic mice, 8 and spontaneously in a proportion of female cotton rats.…”

Section: To the Editormentioning

confidence: 99%

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