Gastric Sarcoidosis: Case Report and Literature Review

Gastric Sarcoidosis Presenting As Dyspepsia

“…Sarcoidosis is a multisystemic disease characterized by the histological presence of noncaseating granulomas, which most commonly manifests in the lungs. Gastrointestinal sarcoidosis is rare and usually asymptomatic, with only 0.1%-0.9% of all cases displaying symptoms [7]. The most commonly involved organ is the stomach, which is present in 10% of cases with GI involvement [8].…”

Gastric Adenocarcinoma at the Sites of Gastric Sarcoidosis: A Case Report

“…Sarcoidosis is characterized by the formation of non-caseating granuloma in the involved tissues. Biopsies and histopathologic examination of the suspected lesions are necessary to confirm the diagnosis and rule out other diseases like H. pylori gastritis, tuberculosis, and fungal infections [8]. In terms of treatment, corticosteroids are indicated when the disease is symptomatic with documented response rate up to 66% [6].…”

Esophageal Sarcoidosis: A Review of Cases and an Update

“…Identification of granulomas should lead the physician to rule out other diseases such as Crohn's disease, tuberculosis, histoplasmosis, adenocarcinoma, foreign body causing a foreign body reaction, and tertiary syphilis. A review of 42 patients who were diagnosed with granulomas on gastric biopsy by Shapiro et al [61] found the most common diagnosis to be Crohn's disease in 55% followed by sarcoidosis in 21% [62]. A barium swallow study can provide valuable information regarding the status of the esophageal sphincters and peristalsis.…”