Gastric recurrence of a primary colon plasmacytoma: staging and evaluating response to therapy with 18F-FDG PET/CT

Abstract

ABSTRACT.A 53-year-old male with a remote history of colon adenocarcinoma presented with weakness, severe anaemia and an actively bleeding ulcerated lesion in the stomach. An 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT showed FDG-avid masses in the stomach and mesentery, which were biopsied to reveal an unsuspected diagnosis of plasmacytoma. The original colon tumour pathology was identical and this prompted its re-evaluation to a primary colon plasmacytoma. The patient was treated with chemotherapy and a follow-up PET/CT scan showed complete resolution of the gastric and mesenteric masses. 18F-FDG PET/CT is useful in the restaging and follow-up of this very rare extramedullary plasmacytoma.

18F-fluorodeoxyglucose positron emission tomography/computed tomography imaging of extra-medullary plasmacytoma of the ovary

“…FDG PET scan is a useful tool in diagnosing and managing extramedullary plasmacytomas as reported previously. [ 1 2 3 4 5 6 7 ] This interesting case also illustrates the utility of FDG PET/CT in the evaluation of extramedullary plasmacytomas.…”

Gastric adenocarcinoma concurrent with paravertebral plasmacytoma: A case report

“…Therefore, our case of EMP concurrent with another type of malignant tumor was rare. Makis et al (11) reported a case of gastric and mesenteric plasmacytoma occurring following surgery for colonic carcinoma. However, the two carcinoma types did not exist at the same time in this case.…”

Plasmocitoma Extramedular Primario Colorrectal

“…La descripción de la pieza operatoria (resección de colon) informa 2 tumoraciones polipoides de 5 x 3 cm y 13 x 9 cm. discusión El presente caso de PEM en recto es muy raro, representa aproximadamente el 7% de todas las neoplasias de células plasmáticas [7][8][9][10] habiéndose encontrado en la bibliografía sólo 32 casos reportados hasta el 2008 5 . Los PEM tienen una edad de presentación promedio de 58 años con una relación hombre mujer de 1.63: 1 respectivamente 11 .…”

“…El plasmocitoma se divide en 2 subtipos; el plasmocitoma solitario del hueso y el plasmocitoma extramedular solitario (PEM) 3 El PEM es una acumulación de células plasmáticas monoclonales localizada 4 , representa el 3% de las neoplasias de este tipo de células, presentándose principalmente en la vía aerodigestiva 5,6 . Sin embargo, un aproximado de 7% se presenta en el tracto gastrointestinal [7][8][9][10] ; principalmente en intestino delgado y estómago. Su presencia en el colon y recto está limitada a 32 casos hasta el 2008 5 , por lo que es poco frecuente.…”