Gastric Outlet Obstruction as the Initial Presentation of Upper Tract Urothelial Carcinoma

Andersen, Karl; Burroughs, Sarah; Munis, Assad; Hoff, Ryan T.; Shapiro, Alan

doi:10.1155/2020/8850062

Cited by 2 publications

(4 citation statements)

References 7 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Metastatic spread of urothelial carcinoma to the gastrointestinal tract is rare and tends to involve the rectum in bladder cancer (8). Upper gastrointestinal symptoms, such as vomiting and epigastric pain due to duodenal obstruction in our specific case, are rare because extrinsic malignancy of the duodenum in urothelial cancers of the upper urinary tract and bladder is uncommon, with few documented cases (9)(10)(11). Tokunaga et al (9) reported two cases of bladder cancer in which abnormal perirectal tissue was initially identified and classified as stage M0.…”

Section: Discussionmentioning

confidence: 95%

“…Subsequently, both cases evolved with the development of RF adjacent to the duodenal wall, although less pronounced than in our study. On the other hand, Andersen et al (11) described a case of UC of the renal pelvis with retroperitoneal extension leading to duodenal obstruction. Similarly, Iwamoto et al (10) documented a case in which periduodenal tissue was detected and reported as inflammatory changes unrelated to the primary tumor, with the final diagnosis made postmortem.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Luengo,

Salmerón,

Medina

et al. 2024

Oncol Lett

View full text Add to dashboard Cite

Retroperitoneal fibrosis, a rare and often idiopathic condition, poses significant diagnostic challenges. While most cases are considered idiopathic or immune-mediated, a small but important proportion are associated with malignant neoplasms, with implications for prognosis and management. The present study describes the case of a 69-year-old man who presented to the emergency department of the Virgen de las Nieves University Hospital (Granada, Spain), with a 2-week history of epigastric pain, vomiting and altered bowel habits. Laboratory investigations revealed previously undiagnosed renal insufficiency. An abdominal computed tomography (CT) scan showed extensive diffuse retroperitoneal infiltration extending from the periduodenal region to the pubic bone, resulting in gastric dilatation and hydronephrosis. A CT-guided retroperitoneal biopsy was performed and pathology confirmed the presence of urothelial carcinoma. This diagnosis led to the initiation of a chemotherapy regimen consisting of carboplatin and gemcitabine specifically designed for urothelial carcinoma. A follow-up 18F-FDG PET scan performed 6 months later showed a partial functional response. This case illustrates a rare presentation of urothelial carcinoma masked by extensive retroperitoneal fibrosis, and highlights the importance of accurate diagnosis in reducing tumor burden and improving the clinical status of patients.

show abstract

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Luengo,

Salmerón,

Medina

et al. 2024

Oncol Lett

View full text Add to dashboard Cite

show abstract

“…To our knowledge, only 12 cases of MGOO caused by UTUC, including 8 case reports (Table S1) and 4 cases from cohort studies (Table 1 and Fig. S1), have been reported in the literature 4–11 . Based on the analysis of 73 cohort studies, only 4 of 5046 patients with MGOO were caused by UTUC (0.08%) (Table 1 and Fig.…”

Section: Discussionmentioning

confidence: 99%

“…S1 ), have been reported in the literature. 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 Based on the analysis of 73 cohort studies, only 4 of 5046 patients with MGOO were caused by UTUC (0.08%) (Table 1 and Fig. S1 ).…”

Section: Discussionmentioning

confidence: 99%

Renal pelvis cancer with initial symptoms of malignant gastric outlet obstruction

Iwamoto,

Oikawa,

Kukimoto

et al. 2023

IJU Case Reports

View full text Add to dashboard Cite

IntroductionGastric outlet obstruction caused by upper tract urothelial carcinoma is rare.Case presentationA 78‐year‐old man presented to the hospital with nausea and vomiting. No hematuria was observed. Computed tomography revealed a tumor in the right renal pelvis and duodenal stenosis. Gastrojejunostomy was performed to treat the symptoms of the gastric outlet obstruction so that the patient could resume oral intake and outpatient chemotherapy. Chemotherapy was unsuccessful, and the patient died 9 months after the gastrojejunostomy. Histological assessment of an autopsy specimen revealed plasmacytoid urothelial carcinoma with direct infiltration of the duodenal wall, which caused the stenosis.ConclusionAutopsy revealed a right renal pelvis cancer causing gastric outlet obstruction. Early gastrojejunostomy enabled oral intake and outpatient visits.

show abstract

Gastric Outlet Obstruction as the Initial Presentation of Upper Tract Urothelial Carcinoma

Abstract: GOO is often the first sign of advanced upper gastrointestinal neoplasms. The most common neoplasms associated with GOO include gastric, pancreatic, and biliary tract cancers. Urinary tract urothelial carcinoma has been a rarely documented cause of GOO.

Cited by 2 publications

References 7 publications

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Urothelial carcinoma masquerading as retroperitoneal fibrosis: A case report

Renal pelvis cancer with initial symptoms of malignant gastric outlet obstruction

Contact Info

Product

Resources

About