2020
DOI: 10.1101/2020.07.01.183533
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Gastric metabolomics analysis supportsH. pylori’s catabolism of organic and amino acids in both the corpus and antrum

Abstract: AbstractHelicobacter pylori is a chronic bacterial pathogen that thrives in several regions of the stomach, causing inflammation that can vary by site and result in distinct disease outcomes. It is not known, however, whether the host-derived metabolites differ between the two main regions, the corpus and antrum. We thus characterized the metabolomes of mouse gastric corpus and antrum organoids and tissue. The secreted organoid metabolites differed si… Show more

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