Gastric Inflammatory Fibroid Polyp Treated with Helicobacter pylori Eradication Therapy

Abstract

Gastric inflammatory fibroid polyps (IFPs) are rare benign lesions that occur in the distal stomach. We describe a 70-year-old womanwith Helicobacter pyloripositive gastric IFP treated with eradication. Gastroduodenal endoscopy revealed a pyramidal-shaped, broadbased tumor with an ulcerated apex at the antrum.Helicobacter pylori was positive by both histology and tissue culture, and eradication (a proton pump inhibitor, amoxicillin, and clarithromycin) was performed. After 3 months, the tumor morphologically changed and the apex ulcer was markedly enlarged. This case suggests that H. pylori may play a role in the pathophysiology of IFPs. (Internal Medicine 42: 263-267, 2003)

Nonsurgical Root Canal Therapy of Large Cyst-like Inflammatory Periapical Lesions and Inflammatory Apical Cysts

“…H. pylori infection is commonly seen associated with hyperplastic polyps of the stomach. Hyperplastic polyps will regress through programmed cell death after early eradication of H. pylori (68)(69)(70). Hyperplasia of bronchial epithelium in chronic bronchitis caused by infection might regress by apoptosis after elimination of infection (27).…”

Gastric Inflammatory Fibroid Polyp Treated by Endoscopic Submucosal Dissection

“…In this case, it was covered almost completely by normal mucosa. It has been suggested that H. pylori may play a role in the pathophysiology of IFP, however, tests for H. pylori were negative in this case [7]. IFP was strongly suspected based on the findings on endoscopic ultrasonography in this case, and the lesion was resected by ESD.…”

Surgical Resection of a Rare Inflammatory Fibroid Polyp of the Stomach: A Case Review

“…There have been reported associations with chronic atrophic gastritis, but often times the adjacent mucosa is normal [4]. It has been suggested by Nishiyama et al, that there is a relationship between H. Pylori and the development and treatment of inflammatory fibroid polyps [7]. No conclusions have been made as other cases, including the one presented above, have not shown an association with H. pylori [8].…”