Gastric cancer treated in 2002 in Japan: 2009 annual report of the JGCA nationwide registry

Abstract

BackgroundThe Japanese Gastric Cancer Association (JGCA) started a new nationwide gastric cancer registration in 2008.MethodsFrom 208 participating hospitals, 53 items including surgical procedures, pathological diagnosis, and survival outcomes of 13,626 patients with primary gastric cancer treated in 2002 were collected retrospectively. Data were entered into the JGCA database according to the JGCA classification (13th edition) and UICC TNM classification (5th edition) using an electronic data collecting system. Finally, data of 13,002 patients who underwent laparotomy were analyzed.ResultsThe 5-year follow-up rate was 83.3 %. The direct death rate was 0.48 %. UICC 5-year survival rates (5YEARSs)/JGCA 5YEARSs were 92.2 %/92.3 % for stage IA, 85.3 %/84.7 % for stage IB, 72.1 %/70.0 % for stage II, 52.8 %/46.8 % for stage IIIA, 31.0 %/28.8 % for stage IIIB, and 14.9 %/15.3 % for stage IV, respectively. The proportion of patients more than 80 years old was 7.8 %, and their 5YEARS was 51.6 %. Postoperative outcome of the patients with primary gastric carcinoma in Japan have apparently improved in advanced cases and among the aged population when compared with the archival data. Further efforts to improve the follow-up rate are needed.ConclusionsPostoperative outcome of the patients with primary gastric carcinoma in Japan have apparently improved in advanced cases and among the aged population when compared with the archival data. Further efforts to improve the follow-up rate are needed.

Prognostic Factors for Stage IV Gastric Cancer

“…According to the JGCA data, cumulative 5-year survival of stage IV patients was 15.3%, 2 and Korean data also showed similar results with 18%. 3 Moreover, among all stage IV patients, 4% to 9% of them are said to be too advanced with no chance of curative surgery and their prognosis is absolutely poor showing less than 10% at 3 years after diagnosis.…”

“…2 Therefore, we do not have a particular treatment algorithm against stage IV patients at this time. However, we weigh patients' clinical symptoms for decision making.…”

Frequency and clinicopathological features of metastasis to liver, lung, bone, and brain from gastric cancer: A SEER‐based study

“…The 5‐year survival for patients with liver metastasis was 11.4% in Japanese GC patients 35. The median survival times of 3‐4 months after detection of bone metastasis have been reported in some studies36, 37 and the median survival after treatment of brain metastasis was about 3 months 23.…”

Does postoperative morbidity worsen the oncological outcome after radical surgery for gastrointestinal cancers? A systematic review of the literature

“…Albeit recent advancements in surgical techniques and perioperative care, the postoperative morbidity rate is as high as approximately 40% after esophageal cancer surgery,1, 2 and 20–30% after both gastric cancer surgery3, 4, 5 and colorectal surgery 6, 7, 8. Various reports have shown that such postoperative complications frequently reduce the overall survival (OS) as well as cancer‐specific survival after major surgery for cancer 9.…”