Gastric Cancer

Macdonald, John S.; Hundahl, Scott A.; Smalley, Stephen R.; O'Dea, Denise; Mitchell, Edith P.

doi:10.1007/978-3-642-13306-0_5

Cited by 3 publications

(4 citation statements)

References 111 publications

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“…We found male patients were more affected (25/ 40) (62.5%) in comparison with female patients (15/ 40) (37.5%), that undergoes with Macdonald et al [11], who found that gastric cancer are more common in male patients in comparison to female patients.…”

Section: Discussionsupporting

confidence: 87%

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Diagnosis of gastric cancer by MDCT gastrography: diagnostic characteristics and management potential

Zytoon

El-Atfey

Hassanein

2020

Egypt J Radiol Nucl Med

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Background: Gastric cancer is regarded as the fifth most frequent tumor globally but the third most common fatal illness. As early as possible, we diagnose cancer stomach especially at early stages, the higher the rate of life. Nevertheless, most cases are diagnosed at late cases where surgery is not of the same benefit at early stages because of clinically indefinite symptoms. The prospective study goal is to estimate the role of MDCT in diagnosis and staging of cancer stomach. Results: In our study, it was found that there was a high relationship between pathological and CT staging by using MPR. CT with MPR was specific and accurate in diagnosis of all stages of gastric cancer with specificity ranged between 93 and 97% and accuracy ranged between 90 and 92.5%. However, it showed lowest sensitivity in diagnosis of stage 1 of gastric cancer. On the other hand, it showed highest sensitivity (90%) in diagnosis of stage IV as well as we found that MPR and VR of MDCT are much more accurate (92.5%) than multi-detector computed tomography axial images (80%) in the diagnosis of all stages of gastric cancer with the difference between the two sequences was significant (P = 0.009). Conclusion: Our results demonstrate that preoperative MDCT with contrast filling technique for abdomen and pelvis evaluates the local disease process of gastric cancer as well as the potential areas of spread. This information is vital in choosing between palliative or radical surgery. MPR and VR help in the assessment of tumor extension and considered as a highly representative prognostic value. Making it the imaging modality of choice in diagnosis and staging of gastric cancers.

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Section: Discussionsupporting

confidence: 87%

“…On the other hand, MDCT help in evaluation of treatment response. It is also considered as one of the important prognostic factors through tumor extent evaluation [11]. In our study, 40 patients underwent analytical study, correlation, and comparison of MDCT radiological data with histopathologically proved results.…”

Section: Discussionmentioning

confidence: 96%

Diagnosis of gastric cancer by MDCT gastrography: diagnostic characteristics and management potential

Zytoon

El-Atfey

Hassanein

2020

Egypt J Radiol Nucl Med

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show abstract

“…For this reason, adjunctive therapies to surgery have been extensively explored in clinical trials over the last 40 years. 3 Some of these adjunctive therapies have been accepted as standards of care. In North America and western Europe, patients with stages II-IV (M0) disease who have undergone gastrectomy benefit in diseasefree and overall survival from postoperative chemoradiotherapy.…”

Section: See Accompanying Article On Page 4387mentioning

confidence: 99%

“…In North America and western Europe, patients with stages II-IV (M0) disease who have undergone gastrectomy benefit in diseasefree and overall survival from postoperative chemoradiotherapy. 4,5 In patients identified preoperatively as having resectable gastric cancer, pre-and postoperative cytotoxic chemotherapy, 6 a strategy termed perioperative therapy, has been accepted as a standard of care on the basis of results from the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) trial published in 2006 by Cunningham et al 6 Many studies of postoperative adjuvant chemotherapy 3…”

Section: See Accompanying Article On Page 4387mentioning

confidence: 99%