Gastric Amyloidosis—a Case Report

Abstract

Introduction: Amyloidosis are abnormal misfolded proteins that are resistant to degradation. Due to defective metabolism, they may be deposited in various organs causing organ dysfunction. Localized amyloidosis is a rare disorder.Case Presentation: We are describing a case of isolated Gastric amyloidosis who presented with recurrent hematemesis and melena due to gastric ulcers. Gastroscopy revealed Multiple Gastric ulcers of variable sizes and shapes. Biopsy followed by histopathology with Congo red staining revealed Gastric amyloidosis.Conclusion: Amyloidosis is a rare disorder. Localized amyloidosis is much rarer compared to systemic amyloidosis. Compared to systemic amyloidosis, localized amyloidosis has a better prognosis. High level of suspicion is needed to diagnose amyloidosis as a rare case of gastric ulcer.