Gastric Adenocarcinoma Presenting as Gastroduodenal Intussusception and Acute Pancreatitis

Bejjani, Lina El; Hasbany, George; Assaker, Richard; Nicolas, G; Daher, Karim; Koury, Elliott; Zeid, Bassel Abou; Tarabine, Kamal; Zaghrini, Elie; Danawi, Monzer; Elias-Rizk, Tamina; Azar, Riad R.

doi:10.12659/mscr.908778

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7 Extensive literature search to date only yielded reports of 11 cases of such exceptional circumstances, and only 5 cases of acute pancreatitis secondary to gastroduodenal intussusception of gastric GIST (Table 1). [8][9][10][11][12][13][14][15][16][17][18] The mean age of these five patients was 71 years, with a slight female predilection. Three patients had pedunculated GISTs dangling from the fundus, causing intussusception, while the remaining two patients had GIST located in the antrum.…”

Section: Discussionmentioning

confidence: 99%

Gastroduodenal intussusception of a gastrointestinal stromal tumor: a rare cause of acute pancreatitis

et al. 2022

View full text Add to dashboard Cite

Gastrointestinal stromal tumor (GIST) accounts for approximately 1% of all gastrointestinal tract neoplasms. 1 GIST usually presents as an incidental gastric subepithelial lesion during upper endoscopy or abdominal radiologic studies. In symptomatic cases, abdominal pain and gastrointestinal bleeding are common manifestations. Gastrointestinal obstruction is a less frequent presentation, occurring in only 10-30% of patients, 2 while gastroduodenal intussusception and acute pancreatitis are extremely unusual presentations of gastric GIST. This report presents the case of a patient diagnosed with gastric GIST complicated by gastroduodenal intussusception, resulting in acute pancreatitis. CASE REPORTA 55-year-old man presented with worsening epigastric pain and vomiting for 10 days. He reported intermittent abdominal pain for 10 months prior to presentation. Abdominal examination revealed tenderness at the epigastrium. His serum amylase level was 320 U/L, compatible with acute pancreatitis. Abdominal computed tomography (CT) revealed a 4 × 4.7 cm well-defined hyperdense mass in the 2 nd part of the duodenum, compressing the pancreatic head, edematous pancreatic parenchyma, peripancreatic fat stranding, and pancreatic duct dilatation (Fig. 1A, B). Esophagogastroduodenoscopy was significant for abnormal torsion of gastric folds that originated from the gastric fundus, coursed along the lesser curvature, and invaginated into the pyloric canal, thereby blocking the passage of the scope into the duodenal bulb (Fig.

show abstract