1993
DOI: 10.3950/jibiinkoka.96.1861
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Gas Ventilation Through Middle Ear Mucosa

Abstract: The possible effects of gas ventilation via the middle ear mucosa on middle ear pressure changes with N2O inhalation were studied. Sixty-seven ears without otologic problems were selected from among cases undergoing ENT surgery under general anesthesia. Anesthesia was induced by isoflurane or sevoflurane, and inhalation with a gas mixture of 21/min O2 and 31/min N2O was started under controlled respiration via endotracheal tube.Middle ear pressure was measured each minute with tympanometry just before and duri… Show more

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“…Those other gases tend to move from the ME to the blood according to their partial pressure gradient between the ME and the blood, but the velocities of their movement are much slower than that of nitrous oxide. As a result, the ME pressure increases 7,8 . Although the manner of the transition is different between oxygen, carbon dioxide (diffusion‐dependent), and nitrogen(perfusion‐dependent), 9 there has been no active selectivity reported in the tissues such as capillary wall or mucosa in terms of gas transition.…”
Section: Discussionmentioning
confidence: 99%
“…Those other gases tend to move from the ME to the blood according to their partial pressure gradient between the ME and the blood, but the velocities of their movement are much slower than that of nitrous oxide. As a result, the ME pressure increases 7,8 . Although the manner of the transition is different between oxygen, carbon dioxide (diffusion‐dependent), and nitrogen(perfusion‐dependent), 9 there has been no active selectivity reported in the tissues such as capillary wall or mucosa in terms of gas transition.…”
Section: Discussionmentioning
confidence: 99%