“…However, electron-capture or transfer dissociation are better suited for assigning labile PTMs such as O-linked glycosylation or phosphorylation of serines or threonines . A combination of electron-transfer dissociation and CID has been applied for studying cyclotides containing numerous cysteine knots . VUV photoionization has recently been proposed for the identification of multiple PTMs in histones. , In 2019, photodissociation using a UV laser revealed mass spectral signatures of dityrosine cross-linking in peptide dimers …”