Gas-Liquid Chromatographic Determination of Pantothenates and Panthenol

Electrochemical oxidation of provitamin B5, d-panthenol and its analysis in spiked human urine

“…Panthenol has been determined by chromatographic methods [Bui-Nguyen 1984;Kulikov and Zinchenko 2007;Prosser and Shreppad 1969;Nagamallika and Arunadevi 2013]: thin-layer chromatographic determination of panthenol with spectro-fluorimetric detection [Shehat Mostafa et al 2004], fluorimetry, and colorimetric methods for the detection of panthenol [Shehat Mostafa et al 2002].…”

N-Methylimidazole-catalyzed acetylation of hydroxy compounds prior to gas chromatographic separation and determination

“…where D is the diffusion coefficient, (v) the mean flow velocity, w the channel thickness, R the retention ratio (equivalent to Vo/ Vr, the ratio of the column void volume to the peak retention volume) and a coefficient which in most practical cases can be approximated by the limiting form (6) = R3/9…”

“…Resorcinol monoacetate (5) is acetylated in 30 min on a steam bath (4:15 Ac20/pyr); ethyl pantothenate and pantothenol (6) are converted to their acetates by 1:1 Ac20/pvr at room temperature for 1 h. Some phenothiazines containing hydroxy groups were treated with 1:1 Ac20/pyr at room temperature for 3 h (7). Alditols were acetylated with 1:1 Ac20/pvr by refluxing overnight (8).…”

Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations

“…Dexpanthenol as alcohol may be determined by using gas-liquid chromatographic methods [10,11]. Liquid chromatographic methods either directly or after hydrolysis and derivatization with fluorescamine were also reported [12,13].…”