Gas gangrene-like infection withBacillus cereus in a lymphoma patient

Gröschel, D; Burgess, Michael A.; Bodey, Gerald P.

doi:10.1002/1097-0142(197602)37:2<988::aid-cncr2820370256>3.0.co;2-y

Cited by 26 publications

(7 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The potential for B. cereus to mimic clostridial myonecrosis or even streptococcal necrotizing fasciitis should be considered when a patient presents with either of these suspected soft-tissue infections. The mimicry of B. cereus myonecrosis compared to that caused by C. perfringens may in part be attributed to phospholipase activity, which in C. perfringens accounts for increased capillary permeability, platelet aggregation, hemolysis, and myonecrosis (48), all attributes described for B. cereus-induced myonecrosis (58).…”

Section: Gas Gangrene-like Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

Bacillus cereus , a Volatile Human Pathogen

2010

View full text Add to dashboard Cite

SUMMARY Bacillus cereus is a Gram-positive aerobic or facultatively anaerobic, motile, spore-forming, rod-shaped bacterium that is widely distributed environmentally. While B. cereus is associated mainly with food poisoning, it is being increasingly reported to be a cause of serious and potentially fatal non-gastrointestinal-tract infections. The pathogenicity of B. cereus, whether intestinal or nonintestinal, is intimately associated with the production of tissue-destructive exoenzymes. Among these secreted toxins are four hemolysins, three distinct phospholipases, an emesis-inducing toxin, and proteases. The major hurdle in evaluating B. cereus when isolated from a clinical specimen is overcoming its stigma as an insignificant contaminant. Outside its notoriety in association with food poisoning and severe eye infections, this bacterium has been incriminated in a multitude of other clinical conditions such as anthrax-like progressive pneumonia, fulminant sepsis, and devastating central nervous system infections, particularly in immunosuppressed individuals, intravenous drug abusers, and neonates. Its role in nosocomial acquired bacteremia and wound infections in postsurgical patients has also been well defined, especially when intravascular devices such as catheters are inserted. Primary cutaneous infections mimicking clostridial gas gangrene induced subsequent to trauma have also been well documented. B. cereus produces a potent β-lactamase conferring marked resistance to β-lactam antibiotics. Antimicrobials noted to be effective in the empirical management of a B. cereus infection while awaiting antimicrobial susceptibility results for the isolate include ciprofloxacin and vancomycin.

show abstract

Section: Gas Gangrene-like Infectionsmentioning

confidence: 99%

“…From the data reviewed above, it is apparent that B. cereus infections predominate in immunosuppressed patients, while primary cutaneous infections may occur in both immunosuppressed (58,63,76) and nonimmunosuppressed individuals, with the latter usually being associated with traumatic incidents (2,22,42,65).…”

Section: Primary Cutaneous Infectionsmentioning

confidence: 99%

Bacillus cereus , a Volatile Human Pathogen

2010

View full text Add to dashboard Cite

show abstract

“…Gas formation within the tissues was reported in one of the previous cases (Groschel et al, 1976). This is of interest in that in routine laboratory tests, B. cereus, in contrast t o C. perfringens, does not produce gas t o any obvious extent.…”

Section: Discussionmentioning

confidence: 69%

Two gas-gangrene-like infections due to Bacillus cereus

Fitzpatrick¹,

Turnbull

Keane³

et al. 1979

Journal of British Surgery

View full text Add to dashboard Cite

show abstract

“…21 Fulminant necrotizing infection resembling gas gangrene following penetrating trauma were reported by various authors. 22,23 In the above cases, penetrating trauma was implicated as an important factor for these infections .…”

Section: Cutaneous Infections Caused By B Cereusmentioning

confidence: 99%

Bacillus cereus as a nongastrointestinal pathogen

Pavani

2014

Int J Res Med Sci

View full text Add to dashboard Cite

The potential of Bacillus cereus to cause systemic infections is of serious concern. Apart from Gastrointestinal infections, it causes respiratory tract infections, nosocomial infections, eye infections, CNS infections, cutaneous infections, endocarditis, osteomyelitis and urinary tract infections. The potential of this bacterium to cause life threatening infections has increased. Trauma is an important predisposing factor for Bacillus cereus infections. The maintenance of skin and mucous membrane integrity limits infection by this microorganism .

show abstract

Gas gangrene-like infection withBacillus cereus in a lymphoma patient

Cited by 26 publications

References 15 publications

Bacillus cereus , a Volatile Human Pathogen

Bacillus cereus , a Volatile Human Pathogen

Two gas-gangrene-like infections due to Bacillus cereus

Bacillus cereus as a nongastrointestinal pathogen

Contact Info

Product

Resources

About