The response of a gas, confined in a microchannel and subject to to instantaneous (small-amplitude) motion of its boundaries in the normal direction, is considered. The problem is formulated using the Bhatnagar, Gross and Krook (BGK) kinetic model, and solved for the entire range of Knudsen (Kn) numbers, combining analytical (collisionless and continuum-limit) solutions with numerical (linearized BGK) calculations. In difference from most existing studies, the case of non-periodic boundary actuation and system approach to equilibrium is investigated. Gas rarefaction is shown to have a "damping effect" on equilibration process, with the time required for equilibrium shortening with increasing Kn. Oscillations in hydrodynamic quantities, characterizing gas response in the continuum limit, vanish in collisionless conditions. Comparison between analytical and numerical solutions indicates that the collisionless description predicts the system behavior exceptionally well for all systems of the size of the mean free path and somewhat larger, in cases where boundary actuation acts along times shorter than the ballistic time scale. The continuum-limit solution, however, should be considered with care at early times near the location of acoustic wavefronts,