Gas exchange and pulmonary haemodynamic responses to fat emulsions in acute respiratory distress syndrome

Abstract

The administration of LCT emulsion given at a slow rate did not alter arterial oxygenation because of the beneficial effect of a high cardiac output, hence offsetting the detrimental effect of increased O2 consumption.

The Acute Respiratory Distress Syndrome: Role of Nutritional Modulation of Inflammation Through Dietary Lipids

“…58 -61 The negative effects of LCT emulsions on both immune status and oxygenation seem to be associated with a rapid infusion rate. 62,63 Although more gradual administration appears to be better tolerated, the potential for harm is still of concern. 57 Various alternative lipid emulsions containing a reduced LCT load have been developed in Europe and seem to have fewer adverse effects.…”

Parenteral Beslenen Yoğun Bakım Hastalarında Soya Yağı, Zeytinyağı ve Mct-Lct Bazlı Nutrisyon Solüsyonlarının Etkilerinin Karşılaştırılması

“…Bu nedenle, Omega-6 yağ asitlerinin anti-inflamatuar etkili, balık yağı kaynaklı Omega-3 yağ asitleri, zeytinyağı kaynaklı Omega-9 yağ asitleri veya orta zincirli yağ asitleri (MCT) ile kombine edilmesi proinflamatuvar etkinin sınırlandırılmasında yararlı olabilir (12)(13)(14)(15)(16)(17).…”

Émulsions lipidiques : indication des différentes émulsions lipidiques

“…Dans une étude ouverte en nutrition parentérale au long cours, le Médialipide ® aurait permis la normalisation des gamma GT à six mois [27]. En ce qui concerne les effets pulmonaires, les études sont là aussi contradictoires, mais difficilement comparables car leur méthodologie était différente [30][31][32][33][34][35][36][37]. Chez les patients ventilés, sans ARDS, il ne semble pas exister d'effet bénéfique à utiliser le Médialipide ® [30,31,37].…”

“…À noter qu'il n'y a pas eu de modification de l'hémodynamique intrapulmonaire. Chez les patients présentant un ARDS, les résultats sont encore plus variables, mais une tendance s'inscrit avec une augmentation du débit cardiaque et une augmentation du rapport PAO 2 /FiO 2 [32][33][34][35][36].…”