Gas chromatography–mass spectrometry identification of photoproducts of hexahydroquinoline derivatives: Potential calcium channel antagonists

Mielcarek, Jadwiga; Matłoka, Agnieszka

doi:10.1016/j.jchromb.2005.01.014

Cited by 2 publications

(1 citation statement)

References 18 publications

(17 reference statements)

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“…The photodegradation rate was found to depend on the type and position of the substituent in the aryl ring. The compounds with alkyl and trifluoromethyl substituent showed the greatest photochemical stability [83,84]. In addition, the compounds having substituents in the ortho position were found much less photostable than the meta isomers.…”

Section: Photostabilitymentioning

confidence: 98%

Fused 1,4-Dihydropyridines as Potential Calcium Modulatory Compounds

Şafak¹,

Şimşek²

2006

MRMC

118

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1,4-Dihydropyridine (1,4-DHP) derivatives nifedipine of which the prototype, are the most popular drugs having calcium antagonistic activity. Fused 1,4-dihydropyridines (DHPs) have also exhibit calcium modulatory activities. In this article, we emphasize calcium channels and fused 1,4-DHP derivatives affecting calcium channels. In addition, the basic considerations of synthesis, metabolism, structure-activity relationships and the latest developments on fused 1,4-DHP derivatives will be reviewed. This review also has extended examples of fused 1,4-DHP derivatives having cited activities synthesized by our group.

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Section: Photostabilitymentioning

confidence: 98%

Fused 1,4-Dihydropyridines as Potential Calcium Modulatory Compounds

Şafak¹,

Şimşek²

2006

MRMC

118

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Current literature in mass spectrometry

2005

J. Mass Spectrom.

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of mass spectrometry. Each bibliography is divided into 11 sections: 1 Books, Reviews & Symposia; 2 Instrumental Techniques & Methods; 3 Gas Phase Ion Chemistry; 4 Biology/Biochemistry: Amino Acids, Peptides & Proteins; Carbohydrates; Lipids; Nucleic Acids; 5 Pharmacology/Toxicology; 6 Natural Products; 7 Analysis of Organic Compounds; 8 Analysis of Inorganics/Organometallics; 9 Surface Analysis; 10 Environmental Analysis; 11 Elemental Analysis. Within each section, articles are listed in alphabetical order with respect to author (5 Weeks journals ‐ Search completed at 10th. Aug. 2005)

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Gas chromatography–mass spectrometry identification of photoproducts of hexahydroquinoline derivatives: Potential calcium channel antagonists

Cited by 2 publications

References 18 publications

Fused 1,4-Dihydropyridines as Potential Calcium Modulatory Compounds

Fused 1,4-Dihydropyridines as Potential Calcium Modulatory Compounds

Current literature in mass spectrometry

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