Gas chromatography — mass spectrometric determination of unsymdimethylhydrazine in soil and water by derivatization with aromatic aldehydes

Abstract

A gas chromatography -mass spectrometric method for determination of unsymdimethylhydrazine (UDMH) in soil and water has been developed. The method is based on derivatization of UDMH with 2-nitrobenzaldehyde, 4-nitrobenzaldehyde, 4-chlorobenzaldeyhde, 4-cyanobenzaldehyde, 4-dimethyaminobenzaldehyde, benzaldehyde and furfuraldehyde, followed by analysis of the derivative using gas chromatography -mass spectrometry. The effect of ambient air and antioxidants (pyrogallol and TiCl,) to absorb dissolved oxygen from the reagents has been investigated. The method proves to be useful for UDMH analysis in soil and water, and has been used for environmental site assessment at a former missile base in Ukraine.On a mis au point une mCthode spectromktrique de masse par chromatographie gazeuse pour la dktermination d'unsymdimCthylhydrazine (UDMH) dans la terre et I'eau. La mkthode s'appuie sur la derivation d'UDMH avec le 2-nitrobenzaldehyde, 4-nitrobenzaldChyde, 4-chlorobenzaldChyde, 4-cyanobenzaldChyde, 4-dimCthyaminobenzaldChyde, benzaldkhyde et furfuraldChyde, suivie de l'analyse des derives au moyen de la spectromktrie de masse par chromatographie gazeuse. On a CtudiC l'effet de l'air ambiant et des antioxydants (pyrogallol et TiCI,) pour absorber I'oxygkne dissous des rkactifs. La methode s'avkre utile pour l'analyse d'UDMH dans l'eau et dans l'air, et elle a Ct C utilisee B des fins d'kvaluation environnementale dans une ancienne base de missiles en Ukraine.

Determination of Dopamine, Glycine, Tryptohan, Valine, Leucine and Isoleucine Using 4-Dimethylaminobenzaldehyde by HPLC in Pharmaceutical Samples

“…The work examines separation and quantitation of 5 analytes. The reagent 4-dimethylaminobenzaldehyde is reported to react with primary amino group containing compound to form Schiff bases [41][42][43][44][45] .…”

“…The development of new reagents for the HPLC determination of biological active amine and amino acids could be of value. 4-Dimetylaminobenzaldehyde (DAB) has been used as derivatizing reagent for the spectrophotometric determination of hydrazine 41 , Lamivudine 42 , bopindolol 43 , GC determination of dimethylhydrazine 44 and HPLC determination of phenylpropanolamine (PPA) 45 . The present work examines 4-dimethylaminobenzaldehyde as derivatizing reagent for HPLC separation and quantitation of dopamine, glycine, tryptophan, valine, leucine and isoleucine and determination of dopamine, tryptophan, valine, leucine and isoleucine from pharmaceutical preparation.…”

Advances of rejected unsymmetrical dimethylhydrazine(UDMH) reuse technology

“…However, UDMH is inflammable, explosive, volatile, mutagenic, and a suspected carcinogenic compound [1][2][3], posing a serious threat to ecological environment and human health. Every year large numbers of UDMH became rejected due to long-term storage, routine maintenance, laboratory sampling and other factors.…”