Gas Chromatography in Screening of Chemicals Related to the Chemical Weapons Convention

Abstract

Various gas chromatographic methods, which are useful for the screening of Chemical Weapons Convention (CWC)‐related chemicals, are described in this section. Choice of columns, detectors, and injection techniques, crucial to the optimization of gas chromatography (GC) as a routine screening tool, are discussed. Also, various identification methods are described. The use of the retention indices (RIs) method allowing identification without the need for an authentic chemical is described in detail. RIs are used as an identification method together with electron ionization mass spectrometry (EIMS) in the on‐site analysis method established by the Organization for the Prohibition of Chemical Weapons (OPCW).

Iron oxide functionalized graphene nano-composite for dispersive solid phase extraction of chemical warfare agents from aqueous samples

“…A rich database is available in the open literature dealing with the analysis of CWC relevant chemicals present in aqueous samples. Amongst various reported techniques, gas chromatography coupled to a suitable detector, such as mass spectrometer (GC-MS), nitrogen-phosphorus detector (GC-NPD) and flame photometry (GC-FPD) is the most preferred one [5,6]. The analytical protocol for gas chromatographic analysis demands an efficient sample preparation step to transfer the desired analytes from aqueous samples to a GC compatible organic solvent.…”