Gas Chromatography/Electron Ionization Mass Spectrometric Analysis of Oligomeric Polyethylene Glycol Mono Alkyl Ethers

Abstract

Polyethylene Glycol Monoalkyl Ethers, C x H 2x+1 (OC 2 H 4 ) n OH, (PEGMAE), are polar compounds like Polyethylene Glycols (PEG) and they undergo microbial degradation which produces toxic substances that are potentially dangerous to the environment. Therefore, the purpose of this study is to carry out proper identification and characterization of these compounds. The Electron Ionization (EI) and Chemical Ionization (CI) spectra of various PEGMAE were obtained by Gas Chromatography/Mass Spectrometry (GC/MS) and were used to identify and characterize these compounds. The characteristic cleavages in the EI and CI reactions of PEGMAEs were also studied. The results obtained showed that the methane CI mass spectra of the PEGMAE contain MH + ions and fragment ions similar to those found in their EI mass spectra. The relative abundances of the MH + ions are low, variable and increase with increasing sample size across the chromatographic peaks; but do not increase with increasing x or n. The base peaks of the low mass oligomers (x≤3) are PEG related (e.g., m/z 45, 59) but those of higher mass oligomers (x≥4) include the ion at m/z 63 (HOC 2 H 4 OH) H + or m/z 107 (HO (C 2 H 4 O) 2 H) H + . There are no (MH-H 2 O) + ions or protonated dimer ions (n≥2, x≥2) in the spectra of PEGMAE. The Relative Molar Sensitivities (RMS) or the Relative Sensitivity per Gram (RSG) increases linearly with molecular polarizabilty or molecular weight with a non-zero intercept.

Design, synthesis and characterization of a PEGylated stanozolol for potential therapeutic applications

“…Conversely, it almost fits perfectly with a compound having a minimal formula C5H13NO2 2.2.7.). This data fits with the finding of Onigbinde et al (2013), who found that methane positive-ion mode chemical ionization of PEGs gives rise to spectra in which the peaks consist mostly of MH + , (C2H4O)nH + , (H(OC2H4)nOH)H2 + , and CH3(OC2H4)n + ions and small amount of C2H5OC2H4 + ions (Onigbinde et al, 2013).…”

Solid Polymer Electrolytes for Lithium Metal Battery via Thermally Induced Cationic Ring-Opening Polymerization (CROP) with an Insight into the Reaction Mechanism

“…In addition, we have also observed the peaks corresponding to CO 2 (AMU 16, 28, and 44), which appeared only at a temperature above 160 °C. The obtained results (Table S1) were in agreement with the reported literature. , …”

“…The obtained results (Table S1) were in agreement with the reported literature. 60,61 The TGA−MS analysis was further carried out on the crosslinked P95 polymer electrolyte sample, and the result is reported in Figure 3B and Table S1, which exhibited more or less similar peaks corresponding LiBF 4 and PEGDGE. The major change for P95 from the oligomer and the salt was that the BF 3 peak was absent in the polymer sample.…”