Gas-Chromatographische Identifizierung und quantitative Bestimmung von Morphin, Codein, Thebain, Papaverin und Narcotin in Opium Extrakt

Simultaneous determination of opiates by circular dichroism

“…Gas and liquid chromatographic methods have been studied extensively in more recent years (11)(12)(13)(14)(15)(16)(17)(18). Of these, liquid chromatographic methods appear to hold the most promise for routine quantitative analyses, since sample preparations are less involved.…”

Separation of five major alkaloids in gum opium and quantitation of morphine, codeine, and thebaine by isocratic reverse phase high performance liquid chromatography

“…Tetraethylene glycol dimethacrylate (TEGDMA) is used as a cross-linking agent in some polymer formulations (1, 2). Hydroquinone (HQ) and methyl ether of hydroquinone (MEHQ) are used as TEGDMA polymerization inhibitors (3) which must be present at high enough levels to ensure good shelf life and thermal stability during polymer processing, but low enough not to interfere significantly with the cross-linking reaction.…”

“…Steady progress in the use of various chromatographic techniques for the analysis of opium and related mixtures has been demonstrated in the literature (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). In 1973 Wu et al (7), using a synthetic mixture of five of the major opium alkaloids, successfully demonstrated that the HPLC technique is potentially useful for such analysis.…”

Gas chromatography

“…Finally, a few interesting and noval applications include the GC determination of penicillins (389), the identification and quantitative determination of microgram amounts of "street heroin" (212, 625), hallucinogens (779), and the drugs in opium extract (64), a GC/MS reference data system with MS base peak index for 133 drugs of abuse (259), and a rapid £<3 hr) analytical method for emergency drug analyses (796). The analysis of the C15-Cse n-alkanes in air particulate matter (377), the identification of spilled residual fuel oils (464), and the characterization of organic components in municipal water supplies (490) are representative of the many applications of GC to pollution studies.…”