Gas chromatographic determination of residual ethylene oxide in gas‐sterilized, medical‐grade plastics

Rudder, D. De; Remon, Jean Paul; Graeve, E De; Severen, R. Van; Braeckman, P

doi:10.1002/jhrc.1240071011

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1986

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“…(aeration time) was determined for the different polymers used in this study (10) ( Table 3). The analysis of EG in sterilized plastics, after a storage period equal to their aeration time, did not unveil any trace of EG.…”

Section: R E S U L T S a N D Discussionmentioning

confidence: 99%

Quantification of Ethylene Chlorohydrin and Ethylene Glycol as Potential Reaction Products in Gas-Sterilized Medical-Grade Plastics

et al. 1986

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A gas chromatographic procedure is described for the quantitative determinations of ethylene chlorohydrin and ethylene glycol in disposable medical‐grade plastics. Both components are isolated by solvent extraction. The lower limit of detection is 1 p.p.m. of ethylene chlorohydrin and 2 p.p.m. of ethylene glycol. Propylene glycol is used as an internal standard. Ethylene oxide residues have to be removed prior to the assay.

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Section: R E S U L T S a N D Discussionmentioning

confidence: 99%