Gas Chromatographic Determination of Metribuzin in Formulations: Collaborative Study

Abstract

A collaborative study was conducted on a gas chromatographic method for determining metribuzin. Two 75% dry flow able and two 42% liquid flowable formulations were analyzed by 18 laboratories. Formulations were extracted by shaking or ultrasonic mixing for 1-5 min with methylene chloride which contained di-n-butyl phthalate as an internal standard. The extracts were injected into a gas chromatograph equipped with an OV-225 column. Peak area ratios and peak height ratios showed no significant difference. The reproducibility coefficient of variation was 0.75% for the 75% formulation and 1.41% for the 42% formulation. This GC method has been adopted official first action.