Ganglioneuroma-paraganglioma of the intradural filum terminale

Abstract

✓ A rare ganglioneuroma-paraganglioma of the filum terminale is reported, and the histological, histochemical, and ultrastructural characteristics of the lesion described. Classification was resolved by the ultrastructure.

Gangliocytic Paraganglioma: Case Report and Review of the Literature

“…Most authors consider GPs to be variants of gastrointestinal tract paragangliomas (18). Paragangliomas may differentiate to other neuroectodermal elements, including neurons and Schwann cells (19). Further evidence of potential for divergent differentiation of neoplastic neuroendocrine cells includes the observation that, when stimulated by nerve growth factor, cell cultures from carcinoid tumor or small cell carcinoma differentiate toward neurons (20).…”

Lumbar intradural paragangliomas: report of two cases

“…PGs were reported for the first time by Miller and Torack in 1970 and called secretory ependymomas (15). In 1972 Lerman et al reported a similar case and named it paraganglioma (13). Spinal paragangliomas comprise 3-4% of all spinal tumors, and about 200 cases of cauda equina PG have been reported in the literature (1,5,29,30).…”

“…PG derives from the embryonic sympathetic and parasympathetic nervous system (13,15,20,28). PGs of the central nervous system have been reported in a few case series, particularly in the cauda equina (24) and spinal nerve roots (13,15). PGs were reported for the first time by Miller and Torack in 1970 and called secretory ependymomas (15).…”

“…They occur commonly in the carotid body, glomus jugulare, mediastinum and retroperitoneum (10). PG derives from the embryonic sympathetic and parasympathetic nervous system (13,15,20,28). PGs of the central nervous system have been reported in a few case series, particularly in the cauda equina (24) and spinal nerve roots (13,15).…”

Paraganglioma of the Cauda Equina Region

“…Lerman and Kaplan 11 were the first to coin the term paraganglioma of the cauda equina in 1972. Lumbar paragangliomas are usually located in the cauda equina and filum terminale region.…”