Ganglio centinela en melanoma maligno cutáneo de tronco y extremidades. Experiencia en el Instituto Nacional de Cancerología, Bogotá, Colombia, 2000–2007

García, Óscar; Vergara, Edgar Mario; Duarte, Carlos M.; Villamizar, Licet; Dı́az, Sandra; Perry, Fernando; Ángel, Javier

doi:10.1016/s0123-9015(11)70060-9

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…The recognized advantages of the sentinel node biopsy include reduction in morbidity resulting from elective lymph node dissection (81%), in the costs of these procedures and in their subsequent complications. Although the surgical mortality of nodal dissections is very low, wound complication rates reported in the literature are close to 40% [38], a percentage similar to that reported in this series.…”

Section: Discussionsupporting

confidence: 87%

See 1 more Smart Citation

Sentinel Node in Cutaneous Squamous Cell Carcinoma of the Trunk and Extremities: Experience in a Latin American Reference Center

Díaz¹,

Molina²,

D³

et al. 2018

JCT

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This paper aims to assess the use of the sentinel node technique in squamous cell carcinoma (SCC) of the trunk and extremities in a Latin American oncology reference center. The descriptive retrospective cohort study included 60 patients diagnosed with SCC of the trunk and extremities, submitted to surgical treatment of the primary tumor and sentinel node biopsy at the breast and soft tissue tumor services of the National Institute of Cancerology (Bogotá, Colombia) over a period of 6 years. The sentinel node was identified in 96.6% (58/60) of the patients. The sentinel node pathology report was negative in 81.7% (49), positive in 15% (9). There were no complications due to the procedure in 85% of the patients. The mean recurrence-free survival time was 8.3 months (CI 95% 5.0 to 11.5 months) in patients with positive sentinel node and 58.6 months (CI 95% 47.8 to 69.3 months) in patients with negative results. Only 4 of 49 patients (8.1%) with negative sentinel node had regional relapse. The study evidenced that the sentinel node technique in patients with high-risk SCC of the trunk and extremities is an adequate staging tool for the lymph node chain, with a low rate of associated complications. This opens an interesting opportunity for prospective cohort studies that can demonstrate statistically significant differences.

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Section: Discussionsupporting

confidence: 87%

“…This technique has been used worldwide in melanoma for more than 10 years, with high success rates of localization, and has displaced the use of methylene blue marking alone. The gold standard is the combination of both techniques (radiocolloid and methylene blue) [37] [38].…”

Section: Discussionmentioning

confidence: 99%