Gamma probe-guided sentinel node biopsy—optimal timing for injection

Lymphoscintigraphy for sentinel node mapping using a hybrid single photon emission CT (SPECT)/CT system in oral cavity squamous cell carcinoma

“…This proximity may result in the SN being obscured by the scatter radiation originating from the injection site. 9,12 Finally, because sentinel nodes in patients with SCC of the oral cavity are located almost exclusively in levels I-III of the neck, close to major neural and vascular structures, such as the internal jugular vein, a supraomohyoid neck dissection may be an appropriate, safer procedure and not much longer than lymphoscintigraphy and SNB.…”

“…This method was based on a previous publication that validated the accuracy of delayed images using this radiopharmaceutical. 9 A 57 Co flood source was placed between the patient and the camera, to define the body contour. A SPECT/ CT emission/transmission study was performed using a hybrid system composed of a dual-head gamma camera with a low-dose X-ray tube installed in its gantry (Discovery VH consisting of a VG8 gamma camera and a Hawkeye X-ray system; General Electric Medical Systems, GEMSI, Haifa, Israel).…”

Axillary Management

“…Several studies have demonstrated no difference in node identifi cation rates using 99m Tc between 2 and 24 hours after injection, a fact that often simplifi es the logistics of scheduling surgery by allowing the injection to take place the night before. [30][31][32] The technique of injection for sentinel node localization has also been examined by several institutions for both the radioactive colloid and the blue dye. Originally, injections were always performed peritumorally based on the concept that this would be the most accurate anatomically.…”

Clinical applications of gamma-detection probes – radioguided surgery

“…However, the use of detection studies for first-time parathyroidism is a controversial point. We also found that in order to obtain better scintigraphy, the breast should be moved to the side and some lateral views should be done [43]. Lymphoscintigraphy scanning was done 20 min, 2 h, 6 h and 24 h after injection.…”