Gamma Knife Thalamotomy for Disabling Tremor

Stereotactic Radiosurgery for Intractable Tremor-Dominant Parkinson Disease: A Retrospective Analysis

“…In addition, 1 patient (3%) improved in bradykinesia, 3 patients (9%) improved in rigidity, and 3 patients (9%) decreased their dosage of dopa after GKT. The results of our study are comparable to other studies of GKT for the treatment of PD tremor [17,18,19,20,21,22,23,24]. …”

“…Ohye et al [22] described outcomes in 59 PD patients, while Witjas et al [25] reported 14 PD patients who were enrolled in a prospective single-blind study. Overall, GKT for PD tremor was associated with a small risk of adverse radiation effects, resulting in temporary hemiparesis or dysphasia [18,19,20,21,22,23,24]. In the present study, we noted improvement in 93.9% of PD patients with a follow-up range of 9-144 months.…”

Stereotactic Radiosurgery for Intractable Tremor-Dominant Parkinson Disease: A Retrospective Analysis

“…In addition, 1 patient (3%) improved in bradykinesia, 3 patients (9%) improved in rigidity, and 3 patients (9%) decreased their dosage of dopa after GKT. The results of our study are comparable to other studies of GKT for the treatment of PD tremor [17,18,19,20,21,22,23,24]. …”

“…Ohye et al [22] described outcomes in 59 PD patients, while Witjas et al [25] reported 14 PD patients who were enrolled in a prospective single-blind study. Overall, GKT for PD tremor was associated with a small risk of adverse radiation effects, resulting in temporary hemiparesis or dysphasia [18,19,20,21,22,23,24]. In the present study, we noted improvement in 93.9% of PD patients with a follow-up range of 9-144 months.…”

Functional lesional neurosurgery for tremor: a systematic review and meta-analysis

“…target and with all but one of the GK studies45 showing significant improvement, our data confirm the efficacy of this target. In this regard, the PD subgroup analysis is of particular interest, as it confirms the previous perception from decades of functional neurosurgery on the superiority of the V.im.…”

A prospective single-blind study of Gamma Knife thalamotomy for tremor

“…19 The effect of GKT in this series was in stark contrast to the rest of the literature. The authors reported no significant tremor reduction but an improvement in ADL.…”

Stereotactic Radiosurgery for Intractable Tremor-Dominant Parkinson Disease: A Retrospective Analysis

“…In addition, 1 patient (3%) improved in bradykinesia, 3 patients (9%) improved in rigidity, and 3 patients (9%) decreased their dosage of dopa after GKT. The results of our study are comparable to other studies of GKT for the treatment of PD tremor [17,18,19,20,21,22,23,24]. …”

“…Ohye et al [22] described outcomes in 59 PD patients, while Witjas et al [25] reported 14 PD patients who were enrolled in a prospective single-blind study. Overall, GKT for PD tremor was associated with a small risk of adverse radiation effects, resulting in temporary hemiparesis or dysphasia [18,19,20,21,22,23,24]. In the present study, we noted improvement in 93.9% of PD patients with a follow-up range of 9-144 months.…”

Functional lesional neurosurgery for tremor: a systematic review and meta-analysis

“…target and with all but one of the GK studies45 showing significant improvement, our data confirm the efficacy of this target. In this regard, the PD subgroup analysis is of particular interest, as it confirms the previous perception from decades of functional neurosurgery on the superiority of the V.im.…”

A prospective single-blind study of Gamma Knife thalamotomy for tremor

“…19 The effect of GKT in this series was in stark contrast to the rest of the literature. The authors reported no significant tremor reduction but an improvement in ADL.…”

Stereotactic Radiosurgery for Intractable Tremor-Dominant Parkinson Disease: A Retrospective Analysis

“…In addition, 1 patient (3%) improved in bradykinesia, 3 patients (9%) improved in rigidity, and 3 patients (9%) decreased their dosage of dopa after GKT. The results of our study are comparable to other studies of GKT for the treatment of PD tremor [17,18,19,20,21,22,23,24]. …”

“…Ohye et al [22] described outcomes in 59 PD patients, while Witjas et al [25] reported 14 PD patients who were enrolled in a prospective single-blind study. Overall, GKT for PD tremor was associated with a small risk of adverse radiation effects, resulting in temporary hemiparesis or dysphasia [18,19,20,21,22,23,24]. In the present study, we noted improvement in 93.9% of PD patients with a follow-up range of 9-144 months.…”

Functional lesional neurosurgery for tremor: a systematic review and meta-analysis

“…target and with all but one of the GK studies45 showing significant improvement, our data confirm the efficacy of this target. In this regard, the PD subgroup analysis is of particular interest, as it confirms the previous perception from decades of functional neurosurgery on the superiority of the V.im.…”

A prospective single-blind study of Gamma Knife thalamotomy for tremor

“…19 The effect of GKT in this series was in stark contrast to the rest of the literature. The authors reported no significant tremor reduction but an improvement in ADL.…”