Abstract:Background
Glomus tumors are rare and benign hypervascular tumors. Surgery represented the mainstay of their treatment, even if it has been associated with high morbidity and mortality rates. Recently, the treatment shifted to a multimodal approach and Gamma Knife radiosurgery represents one of the treatment options.
Methods
Authors retrospectively analyzed the clinical and radiological outcome of a series of patients who underwent Gamma Knife radiosurgery for glomus tumors.
Results
Thirty patients underwent G… Show more
“…In addition, radiosurgical and multidisciplinary treatment options for other paragangliomas should be investigated as well and may be included in one large prospective trial. Considering our findings, similar long‐term experiences with GK, and the possibility to treat extracranial lesions, RRS may be suitable for the treatment of other head and neck paragangliomas than GJTs 59 …”
Section: Discussionsupporting
confidence: 67%
“…Considering our findings, similar long-term experiences with GK, and the possibility to treat extracranial lesions, RRS may be suitable for the treatment of other head and neck paragangliomas than GJTs. 59…”
Background: Glomus jugulare tumors (GJTs) are challenging to treat due to their vascularization and location. This analysis evaluates the effectiveness and safety of image-guided robotic radiosurgery (RRS) for GJTs in a multicenter study and reviews the existing radiosurgical literature. Methods: We analyzed outcome data from 101 patients to evaluate local control (LC), changes in pretreatment deficits, and toxicity. Moreover, radiosurgical studies for GJTs have been reviewed. Results: After a median follow-up of 35 months, the overall LC was 99%. Eighty-eight patients were treated with a single dose, 13 received up to 5 fractions. The median tumor volume was 5.6 cc; the median treatment dose for single-session treatments is 16 Gy, and for multisession treatments is 21 Gy. Fifty-six percentage of patients experienced symptom improvement or recovered entirely. Conclusions: RRS is an effective primary and secondary treatment option for GJTs. The available literature suggests that radiosurgery is a treatment option for most GJTs.
“…In addition, radiosurgical and multidisciplinary treatment options for other paragangliomas should be investigated as well and may be included in one large prospective trial. Considering our findings, similar long‐term experiences with GK, and the possibility to treat extracranial lesions, RRS may be suitable for the treatment of other head and neck paragangliomas than GJTs 59 …”
Section: Discussionsupporting
confidence: 67%
“…Considering our findings, similar long-term experiences with GK, and the possibility to treat extracranial lesions, RRS may be suitable for the treatment of other head and neck paragangliomas than GJTs. 59…”
Background: Glomus jugulare tumors (GJTs) are challenging to treat due to their vascularization and location. This analysis evaluates the effectiveness and safety of image-guided robotic radiosurgery (RRS) for GJTs in a multicenter study and reviews the existing radiosurgical literature. Methods: We analyzed outcome data from 101 patients to evaluate local control (LC), changes in pretreatment deficits, and toxicity. Moreover, radiosurgical studies for GJTs have been reviewed. Results: After a median follow-up of 35 months, the overall LC was 99%. Eighty-eight patients were treated with a single dose, 13 received up to 5 fractions. The median tumor volume was 5.6 cc; the median treatment dose for single-session treatments is 16 Gy, and for multisession treatments is 21 Gy. Fifty-six percentage of patients experienced symptom improvement or recovered entirely. Conclusions: RRS is an effective primary and secondary treatment option for GJTs. The available literature suggests that radiosurgery is a treatment option for most GJTs.
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