“…To understand the nature of the effect, we considered a number of previous studies which had showed that released-active form of antibodies to IFN-g significantly augmented production of IFN-g in both humans and animals [Sherstoboev et al, 2003;Tarasov and Dugina, 2008;Epstein, 2009;Obraztsova et al, 2009;Zhavbert and Dugina, 2013]. Generally, IFN-g plays an important role in the recovery from flu infection by helping to eliminate the virus [Wiley et al, 2001;Bruder et al, 2006;Prabhu et al, 2013;Killip et al, 2015] which means that the regulation of IFN-g level is among the most limiting factors for antiviral host response [Khoufache et al, 2009]. It has been established that AC's influence on the interferon system involves triggering the mechanisms of innate and acquired immunity thus providing the antiviral and immunomodulatory effects, stimulation of the host's defense mechanisms against the virus that is indicative of its pharmacological activity [Epstein, 2009;Tarasov et al, 2012;Epstein, 2013;Zhavbert and Dugina, 2013; Gavrilova and Tarasov, 2014]; which is important in cases of recurrent influenza infection [Wiley et al, 2001;Bruder et al, 2006;Prabhu et al, 2013].…”