Gamma-aminobutyric acid coupled with copper ion stress stimulates lipid production of green microalga Monoraphidium sp. QLY-1 through multiple mechanisms

Li, Ximing; Gu, Dan; You, Jinkun; Qiao, Tengsheng; Yu, Xuya

doi:10.1016/j.biortech.2022.127091

Cited by 12 publications

(1 citation statement)

References 47 publications

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“…Stress induction can also enhance lipid production, but biomass is simultaneously depressed in microalgae. Therefore, the above-mentioned factors are usually combined with stress induction to achieve dual enhancement of lipid and biomass [71][72][73][74][75][76].…”

Section: Lipid Induction Strategies In Microalgaementioning

confidence: 99%

Towards Lipid from Microalgae: Products, Biosynthesis, and Genetic Engineering

Xin,

Wu,

Miao

et al. 2024

Life

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Microalgae can convert carbon dioxide into organic matter through photosynthesis. Thus, they are considered as an environment-friendly and efficient cell chassis for biologically active metabolites. Microalgal lipids are a class of organic compounds that can be used as raw materials for food, feed, cosmetics, healthcare products, bioenergy, etc., with tremendous potential for commercialization. In this review, we summarized the commercial lipid products from eukaryotic microalgae, and updated the mechanisms of lipid synthesis in microalgae. Moreover, we reviewed the enhancement of lipids, triglycerides, polyunsaturated fatty acids, pigments, and terpenes in microalgae via environmental induction and/or metabolic engineering in the past five years. Collectively, we provided a comprehensive overview of the products, biosynthesis, induced strategies and genetic engineering in microalgal lipids. Meanwhile, the outlook has been presented for the development of microalgal lipids industries, emphasizing the significance of the accurate analysis of lipid bioactivity, as well as the high-throughput screening of microalgae with specific lipids.

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