“…This personalized approach to first-line treatment selection could eliminate the practice of requiring all patients to not respond to a behavioral therapy before granting access to more effective obesity treatment options. 15 What patients are most likely to respond to low-intensity behavioral interventions? These approaches may be ideal for patients hesitant to engage with more intensive lifestyle therapy, medical or surgical treatment, those with recent weight gain, those who recently exceeded a BMI threshold (eg, BMI of 30), or those with episodic weight gain due to a timelimited event (eg, postpartum weight retention, medicationinduced weight gain, postinjury weight gain).…”