Gallstone Disease: Epidemiology, Risk Factors, Clinical Features, Prevention

Вахрушев, Я. М.; Хохлачева, Н. А.

doi:10.20514/2226-6704-2016-6-3-30-35

Cited by 16 publications

(9 citation statements)

References 9 publications

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“…Ранний дебют заболевания у коренных американских индейцев детерминирован уникальной генетикой и не опровергает данной закономерности. В то же время ряд авторов отмечают тенденцию к омоложению ЖКБ в иных популяциях [10,11]. Данные эпидемиологического исследования и параметры ретроспективного анализа пациентов в когорте позволяют выделить часто встречающиеся признаки.…”

Section: Discussionunclassified

Conservatism and divergence in the semiotics cholelithiasis

Штыгашева

Агеева

Chmykhalo

2023

jour

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The aim of the study was to analyze the patterns associated with the risk of developing gallstone disease. Material and methods. The selection of signs of metabolic syndrome among patients of the hospital contingent with cholelithiasis, depending on gender and age, was carried out. There are 271 patients in the general population, of which 227 are women and 49 are men. Statistical processing of research results using the Statistica 8.0 applied software package. Results. Differences in etiology and pathogenesis lead to divergence of the phenotype of patients with cholelithiasis. At the same time, the conservatism of significant risk factors for the development of the disease remains. These include ethnic and sexual dimorphism: Caucasians are twice as likely to suffer from gallstone disease than the Khakass (7.3 and 3.4%, respectively). The incidence of gallstones in women is 8.6% (Caucasians - 10.9%; Khakaski - 6.2%). The indicators for women are 4.6 times higher than for men - 1.9% (Caucasians - 2.5%; Khakass - 1.3%). Older age: after 60 years, the number of patients increases exponentially, gender differences decrease. In the rating of comorbidities, the following are most often recorded: abdominal obesity (92.3% of patients), excess body weight (87.8%); violation of carbohydrate metabolism (86.4%), hypertension (81.7%), atherogenic dyslipidemia (50.6%) and NAFLD (23.6%). Conclusion. Together with conservative factors of susceptibility to gallstones that cannot be modified (age increase, female sex, heredity), a pathological phenotype known as metabolic syndrome is often formed. An increase in the frequency of gallstones is associated with variable combinations of metabolic syndrome components. Early detection of these signs can be used to predict and prevent the disease, since they are all modified to one degree or another. In addition, along with the conventional criteria for metabolic syndrome, the expression of gallstone disease has been established, which makes it possible to consider it a full-fledged sign.

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Section: Discussionunclassified

Conservatism and divergence in the semiotics cholelithiasis

Штыгашева

Агеева

Chmykhalo

2023

jour

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“…Introduction. In Ukraine, the incidence of cholelithiasis (CHS) is 10% of the population (Vakhrushev et al, 2016). In the US, CHS is diagnosed in 14-18% of the population, and in 80% of cases with an asymptomatic course.…”

Section: Rehabilitation Prognosis For Patients After Laparoscopic Cho...mentioning

confidence: 99%

“…The incidence rate among women is 2-3 times higher than among men. This is associated with the influence of estrogens on lithogenic processes, a decrease in the contractile function of the gallbladder, which is observed, in particular, in the climacteric period in women, while in men hormonal changes do not affect the formation of stones (Vakhrushev et al, 2016). The risk of developing CHS increases in pregnant women, especially with repeated pregnancies, when the formation of calculi in the gallbladder is noted in 5-12% of women (Vakhrushev et al, 2016).…”

Section: Rehabilitation Prognosis For Patients After Laparoscopic Cho...mentioning

confidence: 99%

Digital Innovations in the Socio-Economic Sphere

2023

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“…Множество факторов риска различных заболеваний напрямую зависят от самого человека [1,2]. Низкая медицинская культура значительной части населения является существенным препятствием на пути формирования активного поведения по укреплению здоровья [3,4].…”

Section: Introductionunclassified

“…В литературе освещаются вопросы организации школ здоровья для пациентов с различной патологией [10,11], однако нами не найдено информации об организации обучения для пациентов с желчнокаменной болезнью (ЖКБ). Между тем, этот вопрос представляется чрезвычайно важным и актуальным на сегодня в связи с все более широким и год от года возрастающим распространением данной патологии [1,2,6].…”

Section: Introductionunclassified

Education of Patients With Stage I Cholelithiasis at the Health School

Хохлачева

Михайлова

Быстрова

2019

Arhivʺ vnutrennej mediciny

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The education of patients at the health school with the objective to improve the effectiveness of treatment of cholelithiasis and to prevent the gallstone formation was organized.Material and methods. 210 patients with cholelithiasis, stage I, were examined: 123 patients (the follow up group) received therapy due to medical and economic standards and were educated in the health school; 87 patients (the comparison group) received only standard therapy. The examined groups of patients were balanced by gender and age. In verification of the diagnosis, in addition to general clinical data, the results of ultrasound examination of the gallbladder were used. The study of psycho-emotional state, health literacy and medical activity dynamics was performed during treatment. The criteria for evaluating of the effectiveness of education at health school were the results of responses to tests and questionnaires.Results. All patients had abdominal pain and dyspeptic syndromes. The study of psychoemotional status revealed significant increasing of state and trait anxiety and the level of depression. The inclusion of health education in the treatment regimen contributed to a distinct decrease of anxiety, that indicates the normalization of the psycho-emotional status, and leads to the more significant positive dynamics of clinical signs. Gaining additional knowledge about cholelithiasis and its prevention contributed to the increase of patient’s motivation to follow the recommended procedures, diet and rational physical activity.Conclusion. The use of the developed structured program of active education of patients with the cholelithiasis, stage I, as part of complex therapy contributes to the improvement of the therapeutic effect, i.e. the earlier decrease of pain and dyspeptic syndrome, and restoring of psycho-emotional balance. After educational classes, the increase of health literacy, medical activity, motivation to maintain health-preserving behavior was revealed, which lasted for 1 year. Thus, the therapeutic education of patients at the early stage of cholelithiasis in health school is clinically confirmed and promising for the prevention of this disease.

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Gallstone Disease: Epidemiology, Risk Factors, Clinical Features, Prevention

Cited by 16 publications

References 9 publications

Conservatism and divergence in the semiotics cholelithiasis

Conservatism and divergence in the semiotics cholelithiasis

Digital Innovations in the Socio-Economic Sphere

Education of Patients With Stage I Cholelithiasis at the Health School

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