Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity
Dawid Gniazdo,
Wanesa Sasal,
Aleksandra Omelaniuk
et al.
Abstract:The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune … Show more
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