Gallenfluß und maximaler Gallendruck nach kürzerem und längerem Verschluß des Ductus hepaticus bei der Ratte

Waldeck, F; Harth, O.

doi:10.1007/bf01789077

Cited by 9 publications

(1 citation statement)

References 15 publications

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“…This pressure is then sustained for several days [Waldeck and Harth, 1963], One would expect that this increased intrahepatic pres sure would seriously interfere with the low pressure portal circulation. Edlund and Gelin [1962], using vital microscopy, thus found slow, sluggish flow in the liver sinusoids of rats already 2 -3 days after ligation of the bile duct.…”

Section: Introductionmentioning

confidence: 99%

Blood Volume Partition after Acute Cholestasis in the Rat

Aarseth¹,

Aarseth²,

Bergan³

1976

Eur Surg Res

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A method involving isotope labelling of blood components and then rapid freezing of intact rats, was used for evaluation of the blood content in liver, spleen and gastrointestinal (GI) tract in cholestatic animals. For comparison also another important blood depot, i.e. the lungs, was examined. After 4 days of cholestasis the animals were hypovolemic, however, the partition of blood in the liver and GI tract was unchanged or even increased. In contrast the lung blood volume and the erythrocyte content of the spleen were markedly reduced. Three days later the animals had regained their normal blood volume, but still there was a redistribution of blood from the lungs and spleen to the liver and GI tract. We suggest that during cholestasis the depot function of the splanchnic vessels is disturbed. This might be one factor of importance for development of the hepatorenal syndrome.

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Section: Introductionmentioning

confidence: 99%