Abstract:Zusammenfassung
Anamnese und klinischer Befund Ein 56-jähriger Patient stellte sich mit rezidivierenden rechtsseitigen Oberbauchschmerzen in unserer Sprechstunde vor. Bei sonst allgemeinem Wohlbefinden präsentierte er ein weiches Abdomen bei insgesamt unauffälligem Untersuchungsbefund. Außer einer Appendektomie sowie Exzision eines malignen Melanoms am Ellenbogen vor einigen Jahren bestanden keine weiteren Vorerkrankungen oder Voroperationen.
Untersuchungen Ein bereits extern angefertigtes … Show more
Although malignant melanoma (MM) most frequently tends to metastasize to the regional lymph nodes, liver, lung and brain, several unusual sites of metastasis have been described in the literature. Among these, the metastatic involvement of gallbladder or uterus represents an exceptional event, usually associated with diffuse metastatic disease or observed as an autopsy finding. In this paper, we present two unusual cases of isolated MM metastasis to these anatomic sites, arising in a 71-year-old man and a 54-year-old woman, for whom no information on previous malignancies was known at the time of the histological examination. The clinico-pathologic features are described, emphasizing that MM metastasis must be included in the differential diagnosis when dealing with patients with a previous diagnosis of MM and onset of a novel mass/lesion even at unusual sites.
Although malignant melanoma (MM) most frequently tends to metastasize to the regional lymph nodes, liver, lung and brain, several unusual sites of metastasis have been described in the literature. Among these, the metastatic involvement of gallbladder or uterus represents an exceptional event, usually associated with diffuse metastatic disease or observed as an autopsy finding. In this paper, we present two unusual cases of isolated MM metastasis to these anatomic sites, arising in a 71-year-old man and a 54-year-old woman, for whom no information on previous malignancies was known at the time of the histological examination. The clinico-pathologic features are described, emphasizing that MM metastasis must be included in the differential diagnosis when dealing with patients with a previous diagnosis of MM and onset of a novel mass/lesion even at unusual sites.
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