Gallbladder mucocele in dogs: 30 cases (2000–2002)

Pike, Fred; Berg, John; King, Norval W.; Penninck, Dominique G.; Webster, Cynthia R. L.

doi:10.2460/javma.2004.224.1615

Cited by 158 publications

(335 citation statements)

References 15 publications

(17 reference statements)

Supporting

Mentioning

302

Contrasting

Unclassified

Order By: Relevance

“…Because GBM formation has a breed predilection for Shetland sheepdogs, is reportedly a disease of older dogs, and is suspected to be increasing in incidence, we chose to control for these variables by selecting control dogs on the basis of matching breed and corresponding in age and year of hospital accession as closely as was possible to the dog diagnosed with a GBM. Control dogs were not matched by sex based on the lack of evidence of an association with GBM formation 1, 3, 4, 6…”

Section: Methodsmentioning

confidence: 99%

“…The syndrome was reported as a rare postmortem finding before 10 years ago and has emerged as one of the most commonly recognized causes of gallbladder disease in the dog 1, 2, 3, 4, 5, 6, 7, 8, 9, 10. The extent to which diagnosis of GBM formation can be attributed to increased use of abdominal ultrasonography in dogs is unknown.…”

mentioning

confidence: 99%

“…Surgical removal of the gallbladder carries a good long‐term prognosis for some dogs. However, surgery often is associated with a high mortality rate, with a median 2‐week mortality of 27% (range, 7–45%) 1, 2, 3, 4, 8, 9, 11…”

mentioning

confidence: 99%

See 2 more Smart Citations

Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case‐Control Study

Gookin

Correa

Peters

et al. 2015

Veterinary Internal Medicne

View full text Add to dashboard Cite

BackgroundThe cause of gallbladder mucocele (GBM) formation in dogs currently is unknown. Many available drugs represent a newer generation of xenobiotics that may predispose dogs to GBM formation.ObjectiveTo determine if there is an association between the histologic diagnosis of GBM in dogs and administration of selected drugs.AnimalsEighty‐one dogs with a histologic diagnosis of GBM and 162 breed, age, and admission date‐matched control dogs from a single referral institution.MethodsMedical records of dogs with GBM and control dogs from 2001 to 2011 were reviewed. Owner verification of drug history was sought by a standard questionnaire. Reported use of heartworm, flea, and tick preventatives as well as nonsteroidal anti‐inflammatory drugs, analgesics, corticosteroids, or medications for treatment of osteoarthritis was recorded.ResultsDogs with GBM were 2.2 times as likely to have had reported use of thyroxine (as a proxy for the diagnosis of hypothyroidism) as control dogs (95% confidence interval [CI], 0.949–5.051), 3.6 times as likely to have had reported treatment for Cushing's disease (95% CI, 1.228–10.612), and 2.3 times as likely to have had reported use of products containing imidacloprid (95% CI, 1.094–4.723). Analysis of a data subset containing only Shetland sheepdogs (23 GBM and 46 control) indicated that Shetland sheepdogs with GBM formation were 9.3 times as likely to have had reported use of imidacloprid as were control Shetland sheepdogs (95% CI, 1.103–78.239).Conclusions and Clinical ImportanceThis study provides evidence for an association between selected drug use and GBM formation in dogs. A larger epidemiologic study of Shetland sheepdogs with GBM formation and exposure to imidacloprid is warranted.

show abstract

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case‐Control Study

Gookin

Correa

Peters

et al. 2015

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…1,2 Whether this apparent increase is because of early-detection by improved abdominal ultrasonography, or an absolute increase in disease incidence, is unknown.…”

mentioning

confidence: 99%

“…2,3 Accumulation of viscous mucus within the gall bladder lumen can cause obstruction of the common bile duct (CBD), resulting in partial or complete obstruction. 2 Histologic diagnosis of GM is based on identification of cystic mucinous hyperplasia.…”

mentioning

confidence: 99%

Clinical Findings and Prognostic Factors for Dogs Undergoing Cholecystectomy for Gall Bladder Mucocele

et al. 2013

View full text Add to dashboard Cite

Objective: To report clinical findings and explore prognostic factors for dogs that had cholecystectomy for gall bladder mucocele. Study Design: Retrospective case series. Animals: Dogs (n = 43) with gall bladder mucoceles. Results: Diagnosis of gall bladder mucoceles was confirmed by histopathology and 74% were diagnosed based on preoperative abdominal ultrasonography. Intraoperative evidence of gall bladder rupture was noted in 10 dogs (23%), and 16 (37%) had evidence of previous leakage in the abdominal cavity. One dog had positive bacterial growth from the gall bladder content. The most common histopathologic findings in liver biopsies obtained at surgery were cholangiohepatitis, biliary hyperplasia, or cholestasis. Univariate analysis showed evidence of postoperative hypotension (P = .05) to be significantly negatively associated with survival. Significant difference in mean postoperative serum lactate (P = .034) and postoperative packed cell volume (P = .063) between dogs that survived and died was also noted. Conclusions: Elevations in postoperative serum lactate concentrations and immediate postoperative hypotension in dogs undergoing cholecystectomy for gall bladder mucoceles are associated with poor clinical outcome.Although a recognized disease process for several decades, the incidence of gall bladder mucoceles (GM) in dogs appears to be increasing.

show abstract

Biliary Emergencies

Ludwig

Smarick²

2015

Small Animal Surgical Emergencies

View full text Add to dashboard Cite

Gallbladder mucocele in dogs: 30 cases (2000–2002)

Cited by 158 publications

References 15 publications

Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case‐Control Study

Association of Gallbladder Mucocele Histologic Diagnosis with Selected Drug Use in Dogs: A Matched Case‐Control Study

Clinical Findings and Prognostic Factors for Dogs Undergoing Cholecystectomy for Gall Bladder Mucocele

Biliary Emergencies

Contact Info

Product

Resources

About